Myocardial longitudinal strain, fitness, and heart failure risk factors in young adults

Aims To investigate the relationship between fitness, heart failure (HF) risk factors (age, blood pressure, and obesity), and global/regional myocardial longitudinal strain in young adults undergoing stress testing. Methods Individuals 25–55 years old without any significant medical history, not tak...

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Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-03, Vol.37 (3), p.404-411
Main Authors: Arenas, Ivan A., Podesta, Carlos A., Issa, Omar, Lin, Jeffrey, Brenes, Juan C.
Format: Article
Language:English
Subjects:
2‐D echo
exercise tolerance
heart failure
left ventricular function
obesity
strain
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Summary:Aims To investigate the relationship between fitness, heart failure (HF) risk factors (age, blood pressure, and obesity), and global/regional myocardial longitudinal strain in young adults undergoing stress testing. Methods Individuals 25–55 years old without any significant medical history, not taking medications, and with a normal maximal stress echocardiogram were eligible. Global and regional longitudinal strain (LS) was evaluated by 2D speckle tracking echocardiography. Results One hundred and seventy patients were included, of which 60% were males. The mean age was 43 years old, 49% had optimal blood pressure, and 30% were obese. On average, patients achieved 10.5 (3) METS, and the global LS was −19.9 (3.1) %. Reduced fitness was associated with decreased global longitudinal strain (GLS). Those in the top GLS quartile walked on average 1 minute and 21 seconds longer compared with the lowest quartile (P 
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.14613