Strain predicts left ventricular functional recovery after acute myocardial infarction with systolic dysfunction

• Published in: International journal of cardiology 2020-05, Vol.307, p.1-7
• Main Authors: Ben Driss, Ahmed, Ben Driss Lepage, Caroline, Sfaxi, Anis, Hakim, Maher, Elhadad, Simon, Tabet, Jean Yves, Salhi, Ahmed, Brandao Carreira, Virginie, Hattab, Madjid, Meurin, Philippe, Weber, Hélène, Ou, Phalla, Quignodon, Jean François, Jondeau, Guillaume, Laissy, Jean Pierre
• Format: Article
• Language: English
• Subjects: 2D strain echocardiography; Contrast Media; Gadolinium; Humans; Left ventricular function; Longitudinal strain; Myocardial infarction; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - therapy; Remodeling; Stroke Volume; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Function, Left
• ISSN: 0167-5273; 1874-1754
• DOI: 10.1016/j.ijcard.2020.02.039

Regional and global longitudinal strain (RLS-GLS) are considered reliable indexes of myocardial viability in chronic ischemic patients and prediction of left ventricular (LV) functional recovery after acute myocardial infarction (MI) with preserved left ventricular ejection fraction (LVEF). We tested in the present study whether RLS and GLS could also identify transmural extent of myocardial scar and predict LV functional recovery and remodeling in patients with reduced LVEF after acute MI. Echocardiography and late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) were performed in 71 patients with reduced LVEF (≤45%) after acute MI treated with acute percutaneous coronary intervention. At 8-month follow-up, echocardiography was repeated to determine global LV functional recovery and remodeling. RLS was worse in transmural than in non-transmural infarcted segments (−6.6 ± 6.1% vs −10.3 ± 5.9%, p