Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy

We report blue- and green-emitting two-photon probes derived from naphthalene and fluorene derivatives (as fluorophores) and an endoplasmic reticulum (ER) retrieval peptide (KDEL; as an ER-targeting moiety) that can detect the ER in a live cell by both one-photon and two-photon microscopy (TPM) and...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (25), p.3657-366
Main Authors: Choi, Ji-Woo, Choi, Seung-Hye, Hong, Seung Taek, Kim, Mun Seok, Ryu, Seong Shick, Yoon, Yeo Uk, Paik, Kyu Cheol, Han, Man So, Sim, Taebo, Cho, Bong Rae
Format: Article
Language:English
Subjects:
Chemical compounds
Endoplasmic reticulum
Fluorescence
Microscopy
Naphthalene
Photons
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Summary:We report blue- and green-emitting two-photon probes derived from naphthalene and fluorene derivatives (as fluorophores) and an endoplasmic reticulum (ER) retrieval peptide (KDEL; as an ER-targeting moiety) that can detect the ER in a live cell by both one-photon and two-photon microscopy (TPM) and in a live tissue by TPM. BER-blue and FER-green can detect the endoplasmic reticulum in a live tissue by two-photon microscopy.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc00236d