Fetal open spinal dysraphism repair through a mini‐hysterotomy: Influence of gestational age at surgery on the perinatal outcomes and postnatal shunt rates

Objective To analyze the impact of gestational age (GA) at the time of fetal open spinal dysraphism (OSD) repair through a mini‐hysterotomy on the perinatal outcomes and the infants' ventriculoperitoneal shunt rates. Methods Retrospective study of cases of fetal OSD correction performed from 20...

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Bibliographic Details
Published in:Prenatal diagnosis 2020-05, Vol.40 (6), p.689-697
Main Authors: Peralta, Cleisson F. A., Botelho, Rafael D., Romano, Edson R., Imada, Vanessa, Lamis, Fabrício, Júnior, Ronaldo R., Nani, Fernando, Stoeber, Gerd H., Salles, Antônio A. F.
Format: Article
Language:English
Subjects:
Bypasses
Congenital defects
Fetuses
Gestational age
Health risk assessment
Hindbrain
Impact analysis
Infants
Neural tube defects
Regression analysis
Shunts
Spinal cord
Surgery
Ventricle
Ventricles (cerebral)
Ventriculoperitoneal shunt
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Summary:Objective To analyze the impact of gestational age (GA) at the time of fetal open spinal dysraphism (OSD) repair through a mini‐hysterotomy on the perinatal outcomes and the infants' ventriculoperitoneal shunt rates. Methods Retrospective study of cases of fetal OSD correction performed from 2014 and 2019. Results One hundred and ninety women underwent fetal surgery for OSD through a mini‐hysterotomy, and 176 (176/190:92.6%) have since delivered. Fetal OSD correction performed earlier in the gestational period, ranging from 19.7 to 26.9 weeks, was associated with lower rates of postnatal ventriculoperitoneal shunting (P: .049). Earlier fetal surgeries were associated with shorter surgical times (P: .01), smaller hysterotomy lengths (P
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.5675