Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan

Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyz...

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Bibliographic Details
Published in:Journal of dermatology 2020-05, Vol.47 (5), p.470-475
Main Authors: Chen, Chih‐Yu, Wang, Wei‐Ming, Chung, Chi‐Hsiang, Tsao, Chang‐Huei, Chien, Wu‐Chien, Hung, Chih‐Tsung
Format: Article
Language:English
Subjects:
Adult
Adults
Aged
Anxiety
Asian people
Case-Control Studies
Cohort analysis
Databases, Factual - statistics & numerical data
Female
Follow-Up Studies
Healthy Volunteers
Humans
Incidence
major depressive disorder
Male
manic disorder
Mental depression
Mental disorders
Mental Disorders - epidemiology
Mental Disorders - etiology
Mental Disorders - psychology
Mental Health - statistics & numerical data
Middle Aged
Population-based studies
psychiatric disorders
Quality of Life
Skin diseases
Taiwan - epidemiology
Urbanization
Vitiligo
Vitiligo - complications
Vitiligo - psychology
Young Adult
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Summary:Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyze the association between vitiligo and the risk of psychiatric disorders using a nationwide database in Taiwan. Data were collected from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 1432 subjects with vitiligo and 5728 age‐, sex‐ and index year‐matched controls were enrolled in this study. Patients with vitiligo tend to have more coexisting psychiatric disorders than healthy individuals, regardless of their sex, age group and facility level of care. After adjusting for sex, age, comorbidity, urbanization and facility level of care, the adjusted hazard ratio of overall psychiatric disorders for patients with vitiligo was 2.926 (95% confidence interval [CI], 2.646–3.236; P 
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.15290