Loading…
Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan
Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyz...
Saved in:
| Published in: | Journal of dermatology 2020-05, Vol.47 (5), p.470-475 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23 |
| container_end_page | 475 |
| container_issue | 5 |
| container_start_page | 470 |
| container_title | Journal of dermatology |
| container_volume | 47 |
| creator | Chen, Chih‐Yu Wang, Wei‐Ming Chung, Chi‐Hsiang Tsao, Chang‐Huei Chien, Wu‐Chien Hung, Chih‐Tsung |
| description | Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyze the association between vitiligo and the risk of psychiatric disorders using a nationwide database in Taiwan. Data were collected from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 1432 subjects with vitiligo and 5728 age‐, sex‐ and index year‐matched controls were enrolled in this study. Patients with vitiligo tend to have more coexisting psychiatric disorders than healthy individuals, regardless of their sex, age group and facility level of care. After adjusting for sex, age, comorbidity, urbanization and facility level of care, the adjusted hazard ratio of overall psychiatric disorders for patients with vitiligo was 2.926 (95% confidence interval [CI], 2.646–3.236; P |
| doi_str_mv | 10.1111/1346-8138.15290 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2370531656</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2397428816</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23</originalsourceid><addsrcrecordid>eNqFkblOwzAYgC0EgnLMbMgSCwMBH3EOtqpcRZVYYLZ8lRrSONgOVTcegWfkSUhaYGDBi-Xfnz9Z-gA4xOgMd-sc0zRLCkyLM8xIiTbA4HeyCQaIFiwhKcp3wG4IzwiRkmG0DXYowSRNSzYA7-NaeSOC0dDb8ALdFDZhqWZWRG8V1DY4r40P0NZQ6LaKsBHRmjoGuLBxBt9stJV9chdwCOvuxtULq80pbFzTVqvz5_uHXPmVmzkfYYitXva6B2EXot4HW1NRBXPwve-Bx-urh9FtMrm_GY-Gk0TRkqEkN4JqaqTEkmWY0RQxhHFuFFKGMaIIy3KkFSqnstBCSqKx0lmm0qxgWEtC98DJ2tt499qaEPncBmWqStTGtYETmiNGccayDj3-gz671tfd7zqqzFNSFLinzteU8i4Eb6a88XYu_JJjxPs4vE_B-xR8Fad7cfTtbeXc6F_-p0YHsDWwsJVZ_ufjd5dXa_EXQSibMQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2397428816</pqid></control><display><type>article</type><title>Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan</title><source>Wiley</source><creator>Chen, Chih‐Yu ; Wang, Wei‐Ming ; Chung, Chi‐Hsiang ; Tsao, Chang‐Huei ; Chien, Wu‐Chien ; Hung, Chih‐Tsung</creator><creatorcontrib>Chen, Chih‐Yu ; Wang, Wei‐Ming ; Chung, Chi‐Hsiang ; Tsao, Chang‐Huei ; Chien, Wu‐Chien ; Hung, Chih‐Tsung</creatorcontrib><description>Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyze the association between vitiligo and the risk of psychiatric disorders using a nationwide database in Taiwan. Data were collected from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 1432 subjects with vitiligo and 5728 age‐, sex‐ and index year‐matched controls were enrolled in this study. Patients with vitiligo tend to have more coexisting psychiatric disorders than healthy individuals, regardless of their sex, age group and facility level of care. After adjusting for sex, age, comorbidity, urbanization and facility level of care, the adjusted hazard ratio of overall psychiatric disorders for patients with vitiligo was 2.926 (95% confidence interval [CI], 2.646–3.236; P < 0.001). Among them, the highest adjusted hazard ratios were found for obsessive–compulsive disorder, at 10.790 (95% CI, 9.756–11.932; P < 0.001). Vitiligo is associated with an increased risk of various psychiatric disorders. By providing a better understanding of the psychosocial burden associated with vitiligo, these results emphasize the need to evaluate the mental health of patients with vitiligo by treating physicians.</description><identifier>ISSN: 0385-2407</identifier><identifier>EISSN: 1346-8138</identifier><identifier>DOI: 10.1111/1346-8138.15290</identifier><identifier>PMID: 32124495</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adult ; Adults ; Aged ; Anxiety ; Asian people ; Case-Control Studies ; Cohort analysis ; Databases, Factual - statistics & numerical data ; Female ; Follow-Up Studies ; Healthy Volunteers ; Humans ; Incidence ; major depressive disorder ; Male ; manic disorder ; Mental depression ; Mental disorders ; Mental Disorders - epidemiology ; Mental Disorders - etiology ; Mental Disorders - psychology ; Mental Health - statistics & numerical data ; Middle Aged ; Population-based studies ; psychiatric disorders ; Quality of Life ; Skin diseases ; Taiwan - epidemiology ; Urbanization ; Vitiligo ; Vitiligo - complications ; Vitiligo - psychology ; Young Adult</subject><ispartof>Journal of dermatology, 2020-05, Vol.47 (5), p.470-475</ispartof><rights>2020 Japanese Dermatological Association</rights><rights>2020 Japanese Dermatological Association.</rights><rights>Copyright © 2020 Japanese Dermatological Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23</citedby><cites>FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23</cites><orcidid>0000-0001-7138-7757 ; 0000-0002-3317-5443</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32124495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Chih‐Yu</creatorcontrib><creatorcontrib>Wang, Wei‐Ming</creatorcontrib><creatorcontrib>Chung, Chi‐Hsiang</creatorcontrib><creatorcontrib>Tsao, Chang‐Huei</creatorcontrib><creatorcontrib>Chien, Wu‐Chien</creatorcontrib><creatorcontrib>Hung, Chih‐Tsung</creatorcontrib><title>Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan</title><title>Journal of dermatology</title><addtitle>J Dermatol</addtitle><description>Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyze the association between vitiligo and the risk of psychiatric disorders using a nationwide database in Taiwan. Data were collected from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 1432 subjects with vitiligo and 5728 age‐, sex‐ and index year‐matched controls were enrolled in this study. Patients with vitiligo tend to have more coexisting psychiatric disorders than healthy individuals, regardless of their sex, age group and facility level of care. After adjusting for sex, age, comorbidity, urbanization and facility level of care, the adjusted hazard ratio of overall psychiatric disorders for patients with vitiligo was 2.926 (95% confidence interval [CI], 2.646–3.236; P < 0.001). Among them, the highest adjusted hazard ratios were found for obsessive–compulsive disorder, at 10.790 (95% CI, 9.756–11.932; P < 0.001). Vitiligo is associated with an increased risk of various psychiatric disorders. By providing a better understanding of the psychosocial burden associated with vitiligo, these results emphasize the need to evaluate the mental health of patients with vitiligo by treating physicians.</description><subject>Adult</subject><subject>Adults</subject><subject>Aged</subject><subject>Anxiety</subject><subject>Asian people</subject><subject>Case-Control Studies</subject><subject>Cohort analysis</subject><subject>Databases, Factual - statistics & numerical data</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Healthy Volunteers</subject><subject>Humans</subject><subject>Incidence</subject><subject>major depressive disorder</subject><subject>Male</subject><subject>manic disorder</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Mental Disorders - epidemiology</subject><subject>Mental Disorders - etiology</subject><subject>Mental Disorders - psychology</subject><subject>Mental Health - statistics & numerical data</subject><subject>Middle Aged</subject><subject>Population-based studies</subject><subject>psychiatric disorders</subject><subject>Quality of Life</subject><subject>Skin diseases</subject><subject>Taiwan - epidemiology</subject><subject>Urbanization</subject><subject>Vitiligo</subject><subject>Vitiligo - complications</subject><subject>Vitiligo - psychology</subject><subject>Young Adult</subject><issn>0385-2407</issn><issn>1346-8138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqFkblOwzAYgC0EgnLMbMgSCwMBH3EOtqpcRZVYYLZ8lRrSONgOVTcegWfkSUhaYGDBi-Xfnz9Z-gA4xOgMd-sc0zRLCkyLM8xIiTbA4HeyCQaIFiwhKcp3wG4IzwiRkmG0DXYowSRNSzYA7-NaeSOC0dDb8ALdFDZhqWZWRG8V1DY4r40P0NZQ6LaKsBHRmjoGuLBxBt9stJV9chdwCOvuxtULq80pbFzTVqvz5_uHXPmVmzkfYYitXva6B2EXot4HW1NRBXPwve-Bx-urh9FtMrm_GY-Gk0TRkqEkN4JqaqTEkmWY0RQxhHFuFFKGMaIIy3KkFSqnstBCSqKx0lmm0qxgWEtC98DJ2tt499qaEPncBmWqStTGtYETmiNGccayDj3-gz671tfd7zqqzFNSFLinzteU8i4Eb6a88XYu_JJjxPs4vE_B-xR8Fad7cfTtbeXc6F_-p0YHsDWwsJVZ_ufjd5dXa_EXQSibMQ</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Chen, Chih‐Yu</creator><creator>Wang, Wei‐Ming</creator><creator>Chung, Chi‐Hsiang</creator><creator>Tsao, Chang‐Huei</creator><creator>Chien, Wu‐Chien</creator><creator>Hung, Chih‐Tsung</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7138-7757</orcidid><orcidid>https://orcid.org/0000-0002-3317-5443</orcidid></search><sort><creationdate>202005</creationdate><title>Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan</title><author>Chen, Chih‐Yu ; Wang, Wei‐Ming ; Chung, Chi‐Hsiang ; Tsao, Chang‐Huei ; Chien, Wu‐Chien ; Hung, Chih‐Tsung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Adults</topic><topic>Aged</topic><topic>Anxiety</topic><topic>Asian people</topic><topic>Case-Control Studies</topic><topic>Cohort analysis</topic><topic>Databases, Factual - statistics & numerical data</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Healthy Volunteers</topic><topic>Humans</topic><topic>Incidence</topic><topic>major depressive disorder</topic><topic>Male</topic><topic>manic disorder</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Mental Disorders - epidemiology</topic><topic>Mental Disorders - etiology</topic><topic>Mental Disorders - psychology</topic><topic>Mental Health - statistics & numerical data</topic><topic>Middle Aged</topic><topic>Population-based studies</topic><topic>psychiatric disorders</topic><topic>Quality of Life</topic><topic>Skin diseases</topic><topic>Taiwan - epidemiology</topic><topic>Urbanization</topic><topic>Vitiligo</topic><topic>Vitiligo - complications</topic><topic>Vitiligo - psychology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Chih‐Yu</creatorcontrib><creatorcontrib>Wang, Wei‐Ming</creatorcontrib><creatorcontrib>Chung, Chi‐Hsiang</creatorcontrib><creatorcontrib>Tsao, Chang‐Huei</creatorcontrib><creatorcontrib>Chien, Wu‐Chien</creatorcontrib><creatorcontrib>Hung, Chih‐Tsung</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Chih‐Yu</au><au>Wang, Wei‐Ming</au><au>Chung, Chi‐Hsiang</au><au>Tsao, Chang‐Huei</au><au>Chien, Wu‐Chien</au><au>Hung, Chih‐Tsung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan</atitle><jtitle>Journal of dermatology</jtitle><addtitle>J Dermatol</addtitle><date>2020-05</date><risdate>2020</risdate><volume>47</volume><issue>5</issue><spage>470</spage><epage>475</epage><pages>470-475</pages><issn>0385-2407</issn><eissn>1346-8138</eissn><abstract>Vitiligo is an autoimmune skin disease that has a major impact on the quality of life of patients. However, a nationwide study of the association between vitiligo and the incidence of inclusive psychiatric diseases has not been conducted in the Asian population. Therefore, this study aimed to analyze the association between vitiligo and the risk of psychiatric disorders using a nationwide database in Taiwan. Data were collected from the National Health Insurance Research Database of Taiwan from 2000 to 2013. In total, 1432 subjects with vitiligo and 5728 age‐, sex‐ and index year‐matched controls were enrolled in this study. Patients with vitiligo tend to have more coexisting psychiatric disorders than healthy individuals, regardless of their sex, age group and facility level of care. After adjusting for sex, age, comorbidity, urbanization and facility level of care, the adjusted hazard ratio of overall psychiatric disorders for patients with vitiligo was 2.926 (95% confidence interval [CI], 2.646–3.236; P < 0.001). Among them, the highest adjusted hazard ratios were found for obsessive–compulsive disorder, at 10.790 (95% CI, 9.756–11.932; P < 0.001). Vitiligo is associated with an increased risk of various psychiatric disorders. By providing a better understanding of the psychosocial burden associated with vitiligo, these results emphasize the need to evaluate the mental health of patients with vitiligo by treating physicians.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>32124495</pmid><doi>10.1111/1346-8138.15290</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-7138-7757</orcidid><orcidid>https://orcid.org/0000-0002-3317-5443</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0385-2407 |
| ispartof | Journal of dermatology, 2020-05, Vol.47 (5), p.470-475 |
| issn | 0385-2407 1346-8138 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2370531656 |
| source | Wiley |
| subjects | Adult Adults Aged Anxiety Asian people Case-Control Studies Cohort analysis Databases, Factual - statistics & numerical data Female Follow-Up Studies Healthy Volunteers Humans Incidence major depressive disorder Male manic disorder Mental depression Mental disorders Mental Disorders - epidemiology Mental Disorders - etiology Mental Disorders - psychology Mental Health - statistics & numerical data Middle Aged Population-based studies psychiatric disorders Quality of Life Skin diseases Taiwan - epidemiology Urbanization Vitiligo Vitiligo - complications Vitiligo - psychology Young Adult |
| title | Increased risk of psychiatric disorders in adult patients with vitiligo: A nationwide, population‐based cohort study in Taiwan |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T14%3A13%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Increased%20risk%20of%20psychiatric%20disorders%20in%20adult%20patients%20with%20vitiligo:%20A%20nationwide,%20population%E2%80%90based%20cohort%20study%20in%20Taiwan&rft.jtitle=Journal%20of%20dermatology&rft.au=Chen,%20Chih%E2%80%90Yu&rft.date=2020-05&rft.volume=47&rft.issue=5&rft.spage=470&rft.epage=475&rft.pages=470-475&rft.issn=0385-2407&rft.eissn=1346-8138&rft_id=info:doi/10.1111/1346-8138.15290&rft_dat=%3Cproquest_cross%3E2397428816%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3950-7ea3d3ebb1b561534050117ec0ce552c25670dc09fb8dabb2d1cd66c46851db23%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2397428816&rft_id=info:pmid/32124495&rfr_iscdi=true |