Clinicopathologic Analysis of Oral and Maxillofacial Solitary Fibrous Tumor

Abstract Objectives The aim of this systematic review was to provide an overview of the oral and maxillofacial solitary fibrous tumor (SFT) in order to determine its clinicopathologic characteristics and biological behavior. Methods We conducted a systematic review in May 2019 in multiple databases....

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Published in:American journal of clinical pathology 2020-06, Vol.154 (1), p.15-22
Main Authors: de Morais, Everton Freitas, Martins, Hélder Domiciano Dantas, Rodrigues, Katianne Soares, de França, Glória Maria, da Silveira, Éricka Janine Dantas, Freitas, Roseana de Almeida
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Female
Head and Neck Neoplasms - pathology
Humans
Male
Middle Aged
Mouth Neoplasms - pathology
Solitary Fibrous Tumors - pathology
Young Adult
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Summary:Abstract Objectives The aim of this systematic review was to provide an overview of the oral and maxillofacial solitary fibrous tumor (SFT) in order to determine its clinicopathologic characteristics and biological behavior. Methods We conducted a systematic review in May 2019 in multiple databases. Cases diagnosed as SFT in the oral cavity and maxillofacial complex were included. Results Seventy-three published articles were included in our systematic review, corresponding to a total of 154 cases. SFT showed a slight female predilection (53.2%), and the cheek mucosa/cheek, tongue, and palate were the most affected anatomical sites. The mean size of SFT in the oral cavity and maxillofacial region at diagnosis was 1.4 cm. Histologic features of malignancy by morphologic analysis (P 
ISSN:0002-9173
1943-7722
1943-7722
DOI:10.1093/ajcp/aqaa027