Chemical Surface Modification of Polymeric Biomaterials for Biomedical Applications

This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overvie...

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Bibliographic Details
Published in:Macromolecular rapid communications. 2020-04, Vol.41 (8), p.e1900430-n/a
Main Authors: Sun, Wei, Liu, Wenying, Wu, Zhaoqiang, Chen, Hong
Format: Article
Language:English
Subjects:
Antifouling substances
Biocompatibility
Biocompatible Materials - chemistry
Biomaterials
biomedical applications
Biomedical materials
Biomedical Research
Brushes
Chemical synthesis
graft polymerization
Grafting
Particle Size
polymeric biomaterials
Polymers
Polymers - chemistry
Substrates
surface modification
Surface Properties
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Summary:This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overview of recent work on the chemical surface modification of polymeric biomaterials, with a focus on “grafting‐to,” “grafting‐from,” and “grafting‐through” strategies, is provided. Finally, some representative cutting‐edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted. On the basis of this literature study, a perspective on future trends in this field is provided. A comprehensive overview of recent work on chemical surface modification of polymeric biomaterials, with a focus on grafting‐to, grafting‐from, and grafting‐through strategies, is provided. Furthermore, some representative cutting‐edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted.
ISSN:1022-1336
1521-3927
DOI:10.1002/marc.201900430