Lignans and Terpenoids from the Leaves of Schisandra chinensis

Fifteen constituents, including one new lignan (schisandroside E) and one new terpenoid (schisandenoid A) as well as nine known lignans and four known terpenoids, were isolated from Schisandra chinensis leaves. The structures of schisandroside E and schisandenoid A were established by entirely metic...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry & biodiversity 2020-04, Vol.17 (4), p.e2000035-n/a
Main Authors: Liu, Guo‐Zhen, Liu, Yan, Sun, Yan‐Ping, Li, Xiao‐Mao, Xu, Zhen‐Peng, Jiang, Peng, Rong, Xiao‐Hui, Yang, Bing‐You, Kuang, Hai‐Xue
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - isolation & purification
Antineoplastic Agents, Phytogenic - pharmacology
biological activity
Biotechnology
Cell Line
Cell Survival - drug effects
Cytotoxicity
Humans
Infrared analysis
Lignans
Lignans - chemistry
Lignans - isolation & purification
Lignans - pharmacology
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Conformation
Mushrooms
NMR
Nuclear magnetic resonance
Plant Extracts - chemistry
Plant Leaves - chemistry
Plant Leaves - metabolism
Schisandra - chemistry
Schisandra - metabolism
Schisandra chinensis
Terpenes
Terpenes - chemistry
Terpenes - isolation & purification
Terpenes - pharmacology
terpenoids
Toxicity testing
Tumor cell lines
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fifteen constituents, including one new lignan (schisandroside E) and one new terpenoid (schisandenoid A) as well as nine known lignans and four known terpenoids, were isolated from Schisandra chinensis leaves. The structures of schisandroside E and schisandenoid A were established by entirely meticulous spectroscopic analysis (NMR, MS, CD, IR and UV). All compounds were tested for cytotoxicity against MGC‐803, Caco‐2 and Ishikawa cell lines. Some compounds showed strong cytotoxicity against these three cancer cell lines with IC50
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202000035