Association between intraoperative nociception and surgical invasiveness in patients undergoing non-cardiac surgery under general anesthesia: a retrospective cohort study

There are several indexes of intraoperative nociception during surgery under general anesthesia. Although a higher degree of surgical invasiveness increases intraoperative nociception, an association between the index of intraoperative nociception and severity of surgical invasiveness has not been r...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical monitoring and computing 2021-05, Vol.35 (3), p.499-503
Main Authors: Ishimoto, Daisuke, Ogata, Hiroki, Miyawaki, Hiroki, Nakamoto, Shiroh, Ueki, Ryusuke, Kariya, Nobutaka, Tatara, Tsuneo, Hirose, Munetaka
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesiology
Cohort analysis
Critical Care Medicine
General anesthesia
Health Sciences
Intensive
Medicine
Medicine & Public Health
Mortality
Original Research
Prediction models
Risk
Statistics for Life Sciences
Surgery
Surgical instruments
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are several indexes of intraoperative nociception during surgery under general anesthesia. Although a higher degree of surgical invasiveness increases intraoperative nociception, an association between the index of intraoperative nociception and severity of surgical invasiveness has not been reported. We hypothesized that there is associations between averaged values of nociceptive response (NR) throughout surgery (mean NR), as the index of intraoperative nociception, and surgical severity codes in the Surgical outcome risk tool (SORT) or procedure risk codes in the Surgical mortality probability model (S-MPM). The primary outcome was the association between mean NR and severity scores of surgical procedure. Hence, a single institutional retrospective cohort study was performed in consecutive patients undergoing non-cardiac surgery under general anesthesia from June 2018 to May 2019. There were significant increases in the three categories of procedure risk in the S-MPM corresponding to the increase in mean NR values in 5090 patients. In the SORT, the highest intensity in the four categories of surgical severity also significantly correlated with the increase in mean NR values. Increasing intensity of intraoperative nociception is likely associated with higher severity codes of surgical invasiveness in prediction models for postoperative morbidity and mortality.
ISSN:1387-1307
1573-2614
DOI:10.1007/s10877-020-00492-0