Predictors of long ECMO runs for congenital diaphragmatic hernia

Although longer ECMO run times for patients with congenital diaphragmatic hernia (CDH) have been associated with worse outcomes, a large study has not been conducted to examine the risk factors for long ECMO runs. The Extracorporeal Life Support Organization (ELSO) Registry from 2000 to 2015 was use...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pediatric surgery 2020-06, Vol.55 (6), p.993-997
Main Authors: Delaplain, Patrick T., Yu, Peter T., Ehwerhemuepha, Louis, Nguyen, Danh V., Jancelewicz, Tim, Stein, James, Harting, Matthew T., Guner, Yigit S.
Format: Article
Language:English
Subjects:
Congenital diaphragmatic hernia (CDH)
Extracorporeal membrane oxygenation (ECMO)
Neonate
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although longer ECMO run times for patients with congenital diaphragmatic hernia (CDH) have been associated with worse outcomes, a large study has not been conducted to examine the risk factors for long ECMO runs. The Extracorporeal Life Support Organization (ELSO) Registry from 2000 to 2015 was used to identify predictors of long ECMO runs in CDH patients. A long run was any duration of ≥14 days. Multivariable logistic regression models were used to examine the association between demographics, pre-ECMO blood gas/ventilator settings, comorbid conditions, and therapies on long ECMO runs. There were 4730 CDH-infants examined. The largest association with long ECMO runs was on-ECMO repair (OR: 3.72, 95% CI: 3.013–4.602, p 
ISSN:0022-3468
1531-5037
DOI:10.1016/j.jpedsurg.2020.02.043