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Incidence of and Risk Factors for Multiple Readmissions after Kidney Transplantation
Unplanned readmission is often used as a surgical quality metric. A subset of kidney transplant recipients undergos multiple readmissions (MRs), although the incidence and risk factors are not well described. The aim of this study was to evaluate risk factors for MR after deceased donor kidney trans...
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Published in: | The American surgeon 2020-02, Vol.86 (2), p.116-120 |
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description | Unplanned readmission is often used as a surgical quality metric. A subset of kidney transplant recipients undergos multiple readmissions (MRs), although the incidence and risk factors are not well described. The aim of this study was to evaluate risk factors for MR after deceased donor kidney transplantation. All patients undergoing deceased donor kidney transplantation at a single center over a three-year period were analyzed via retrospective chart review for factors associated with MR. P values |
doi_str_mv | 10.1177/000313482008600230 |
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A subset of kidney transplant recipients undergos multiple readmissions (MRs), although the incidence and risk factors are not well described. The aim of this study was to evaluate risk factors for MR after deceased donor kidney transplantation. All patients undergoing deceased donor kidney transplantation at a single center over a three-year period were analyzed via retrospective chart review for factors associated with MR. P values <0.05 were considered significant. Of 141 patients, the 30-day readmission rate was 26.2 per cent. MR occurred in 43 (30.5%) patients. Age, race, gender, initial organ function, and dialysis vintage were not associated with MR. Diabetic recipients, those who received basiliximab induction, those with acute rejection, and those with unplanned reoperations were at increased risk for MR. Infection was the most common reason for initial readmission in patients with MR (23.3%). One-year patient survival and death-censored graft survival were reduced for patients with MR. MRs are required for 30 per cent of kidney transplant recipients, primarily because of infection and immunologic causes. Recipients with diabetes and those who have acute rejection are at greatest risk.</description><identifier>ISSN: 0003-1348</identifier><identifier>EISSN: 1555-9823</identifier><identifier>DOI: 10.1177/000313482008600230</identifier><identifier>PMID: 32167042</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Basiliximab - adverse effects ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus - epidemiology ; Dialysis ; Female ; Graft rejection ; Graft Rejection - epidemiology ; Graft Survival ; Health risks ; Humans ; Immunosuppressive Agents - adverse effects ; Incidence ; Infections ; Kidney transplantation ; Kidney Transplantation - mortality ; Kidney Transplantation - statistics & numerical data ; Kidney transplants ; Male ; Middle Aged ; Monoclonal antibodies ; Mortality ; Patient admissions ; Patient Readmission - statistics & numerical data ; Postoperative Complications - epidemiology ; Regression Analysis ; Rejection ; Reoperation - adverse effects ; Reoperation - statistics & numerical data ; Retrospective Studies ; Risk analysis ; Risk Factors ; Survival ; Survival analysis ; Time Factors ; Transplantation ; Transplants & implants ; Variables</subject><ispartof>The American surgeon, 2020-02, Vol.86 (2), p.116-120</ispartof><rights>2020 Southeastern Surgical Congress</rights><rights>Copyright Southeastern Surgical Congress Feb 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-e51f0bb49f971d0553344d3c5de132090d04d93f34fac59110ad33156ef0e7a53</citedby><cites>FETCH-LOGICAL-c371t-e51f0bb49f971d0553344d3c5de132090d04d93f34fac59110ad33156ef0e7a53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32167042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schucht, Jessica</creatorcontrib><creatorcontrib>Davis, Eric G.</creatorcontrib><creatorcontrib>Jones, Christopher M.</creatorcontrib><creatorcontrib>Cannon, Robert M.</creatorcontrib><title>Incidence of and Risk Factors for Multiple Readmissions after Kidney Transplantation</title><title>The American surgeon</title><addtitle>Am Surg</addtitle><description>Unplanned readmission is often used as a surgical quality metric. A subset of kidney transplant recipients undergos multiple readmissions (MRs), although the incidence and risk factors are not well described. The aim of this study was to evaluate risk factors for MR after deceased donor kidney transplantation. All patients undergoing deceased donor kidney transplantation at a single center over a three-year period were analyzed via retrospective chart review for factors associated with MR. P values <0.05 were considered significant. Of 141 patients, the 30-day readmission rate was 26.2 per cent. MR occurred in 43 (30.5%) patients. Age, race, gender, initial organ function, and dialysis vintage were not associated with MR. Diabetic recipients, those who received basiliximab induction, those with acute rejection, and those with unplanned reoperations were at increased risk for MR. Infection was the most common reason for initial readmission in patients with MR (23.3%). One-year patient survival and death-censored graft survival were reduced for patients with MR. MRs are required for 30 per cent of kidney transplant recipients, primarily because of infection and immunologic causes. Recipients with diabetes and those who have acute rejection are at greatest risk.</description><subject>Basiliximab - adverse effects</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Dialysis</subject><subject>Female</subject><subject>Graft rejection</subject><subject>Graft Rejection - epidemiology</subject><subject>Graft Survival</subject><subject>Health risks</subject><subject>Humans</subject><subject>Immunosuppressive Agents - adverse effects</subject><subject>Incidence</subject><subject>Infections</subject><subject>Kidney transplantation</subject><subject>Kidney Transplantation - mortality</subject><subject>Kidney Transplantation - statistics & numerical data</subject><subject>Kidney transplants</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Monoclonal antibodies</subject><subject>Mortality</subject><subject>Patient admissions</subject><subject>Patient Readmission - statistics & numerical data</subject><subject>Postoperative Complications - epidemiology</subject><subject>Regression Analysis</subject><subject>Rejection</subject><subject>Reoperation - adverse effects</subject><subject>Reoperation - statistics & numerical data</subject><subject>Retrospective Studies</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Survival</subject><subject>Survival analysis</subject><subject>Time Factors</subject><subject>Transplantation</subject><subject>Transplants & implants</subject><subject>Variables</subject><issn>0003-1348</issn><issn>1555-9823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMo7rr6BzxIwIuX6qSTNNujLH4sKoKs55JtJtK1265Je_Dfm7J-gIKnMOSZd14exo4FnAuh9QUAoEA5TQGmGUCKsMPGQimV5NMUd9l4AJKBGLGDEFZxlJkS-2yEqcg0yHTMFvOmrCw1JfHWcdNY_lSFV35tyq71gbvW84e-7qpNTfyJjF1XIVRtE7hxHXl-V9mG3vnCmyZsatN0pou_h2zPmTrQ0ec7Yc_XV4vZbXL_eDOfXd4nJWrRJaSEg-VS5i7XwoJSiFJaLJUlgSnkYEHaHB1KZ0qVCwHGIgqVkQPSRuGEnW1zN7596yl0RaxXUh2LUNuHIkWtUepBzYSd_kJXbe-b2G6glMxEVBipdEuVvg3Bkys2vlob_14IKAbnxV_ncenkM7pfrsl-r3xJjsDFFgjmhX7u_hP5AdjYh2w</recordid><startdate>20200201</startdate><enddate>20200201</enddate><creator>Schucht, Jessica</creator><creator>Davis, Eric G.</creator><creator>Jones, Christopher M.</creator><creator>Cannon, Robert M.</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>4U-</scope><scope>7QL</scope><scope>7RV</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20200201</creationdate><title>Incidence of and Risk Factors for Multiple Readmissions after Kidney Transplantation</title><author>Schucht, Jessica ; Davis, Eric G. ; Jones, Christopher M. ; Cannon, Robert M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-e51f0bb49f971d0553344d3c5de132090d04d93f34fac59110ad33156ef0e7a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Basiliximab - adverse effects</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Dialysis</topic><topic>Female</topic><topic>Graft rejection</topic><topic>Graft Rejection - epidemiology</topic><topic>Graft Survival</topic><topic>Health risks</topic><topic>Humans</topic><topic>Immunosuppressive Agents - adverse effects</topic><topic>Incidence</topic><topic>Infections</topic><topic>Kidney transplantation</topic><topic>Kidney Transplantation - mortality</topic><topic>Kidney Transplantation - statistics & numerical data</topic><topic>Kidney transplants</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Monoclonal antibodies</topic><topic>Mortality</topic><topic>Patient admissions</topic><topic>Patient Readmission - statistics & numerical data</topic><topic>Postoperative Complications - epidemiology</topic><topic>Regression Analysis</topic><topic>Rejection</topic><topic>Reoperation - adverse effects</topic><topic>Reoperation - statistics & numerical data</topic><topic>Retrospective Studies</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Survival</topic><topic>Survival analysis</topic><topic>Time Factors</topic><topic>Transplantation</topic><topic>Transplants & implants</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schucht, Jessica</creatorcontrib><creatorcontrib>Davis, Eric G.</creatorcontrib><creatorcontrib>Jones, Christopher M.</creatorcontrib><creatorcontrib>Cannon, Robert M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest - 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Academic</collection><jtitle>The American surgeon</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schucht, Jessica</au><au>Davis, Eric G.</au><au>Jones, Christopher M.</au><au>Cannon, Robert M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Incidence of and Risk Factors for Multiple Readmissions after Kidney Transplantation</atitle><jtitle>The American surgeon</jtitle><addtitle>Am Surg</addtitle><date>2020-02-01</date><risdate>2020</risdate><volume>86</volume><issue>2</issue><spage>116</spage><epage>120</epage><pages>116-120</pages><issn>0003-1348</issn><eissn>1555-9823</eissn><abstract>Unplanned readmission is often used as a surgical quality metric. A subset of kidney transplant recipients undergos multiple readmissions (MRs), although the incidence and risk factors are not well described. The aim of this study was to evaluate risk factors for MR after deceased donor kidney transplantation. All patients undergoing deceased donor kidney transplantation at a single center over a three-year period were analyzed via retrospective chart review for factors associated with MR. P values <0.05 were considered significant. Of 141 patients, the 30-day readmission rate was 26.2 per cent. MR occurred in 43 (30.5%) patients. Age, race, gender, initial organ function, and dialysis vintage were not associated with MR. Diabetic recipients, those who received basiliximab induction, those with acute rejection, and those with unplanned reoperations were at increased risk for MR. Infection was the most common reason for initial readmission in patients with MR (23.3%). One-year patient survival and death-censored graft survival were reduced for patients with MR. MRs are required for 30 per cent of kidney transplant recipients, primarily because of infection and immunologic causes. Recipients with diabetes and those who have acute rejection are at greatest risk.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>32167042</pmid><doi>10.1177/000313482008600230</doi><tpages>5</tpages></addata></record> |
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subjects | Basiliximab - adverse effects Diabetes Diabetes mellitus Diabetes Mellitus - epidemiology Dialysis Female Graft rejection Graft Rejection - epidemiology Graft Survival Health risks Humans Immunosuppressive Agents - adverse effects Incidence Infections Kidney transplantation Kidney Transplantation - mortality Kidney Transplantation - statistics & numerical data Kidney transplants Male Middle Aged Monoclonal antibodies Mortality Patient admissions Patient Readmission - statistics & numerical data Postoperative Complications - epidemiology Regression Analysis Rejection Reoperation - adverse effects Reoperation - statistics & numerical data Retrospective Studies Risk analysis Risk Factors Survival Survival analysis Time Factors Transplantation Transplants & implants Variables |
title | Incidence of and Risk Factors for Multiple Readmissions after Kidney Transplantation |
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