Practical and rapidly-implemented parameters for assessing APAP titration failure

Background This study aimed to show the predictive value of simple polysomnographic parameters including latency of deep sleep (nREM3), latency of rapid eye movement sleep (REM), and minimum oxygen saturation (SpO 2 ) for predicting failure of autoadjusting positive airway pressure (APAP) titration....

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Bibliographic Details
Published in:Sleep & breathing 2021-03, Vol.25 (1), p.49-55
Main Authors: Şahin Duyar, Sezgi, Fırat, Selma, Kara, Türkan, Çelik, Deniz
Format: Article
Language:English
Subjects:
Apnea
Dentistry
Internal Medicine
Latency
Medicine
Medicine & Public Health
Neurology
Otorhinolaryngology
Pediatrics
Pneumology/Respiratory System
REM sleep
Sleep
Sleep Breathing Physiology and Disorders • Original Article
Sleep disorders
Statistical analysis
Titration
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Summary:Background This study aimed to show the predictive value of simple polysomnographic parameters including latency of deep sleep (nREM3), latency of rapid eye movement sleep (REM), and minimum oxygen saturation (SpO 2 ) for predicting failure of autoadjusting positive airway pressure (APAP) titration. Methods Out of 1470 patients with moderate to severe obstructive sleep apnea syndrome (OSAS) who underwent APAP titration between July 1, 2016, and December 31, 2017, 22 patients with titration failure were enrolled in the study. The demographic and polysomnographic characteristics of this group were compared with 44 patients with an adequate APAP titration who were matched with the titration failure group by age, sex, and OSAS severity. The periods between the start of sleep and the start of REM and nREM3 stages were noted as REM latency and nREM3 latency, respectively. Results The between group differences in the parameters including nREM3 latency, REM latency, and minimum SpO 2 during the titration test were statistically significant ( p = 0.004, p = 0.008, p
ISSN:1520-9512
1522-1709
DOI:10.1007/s11325-020-02052-x