Effects of epicardial adipose tissue volume and density on cardiac structure and function in patients free of coronary artery disease

Purpose To determine the association of epicardial adipose tissue (EAT) volume and density with cardiac geometry and function. Methods We included 178 consecutive patients who performed coronary computed tomography angiography but were not diagnosed with coronary artery disease (CAD). The EAT volume...

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Bibliographic Details
Published in:Japanese journal of radiology 2020-07, Vol.38 (7), p.666-675
Main Authors: Lu, Yang, Wang, Tianle, Zhan, Rui, Wang, Xiaoyu, Ruan, Xiwu, Qi, Rongxing, Huang, Sheng
Format: Article
Language:English
Subjects:
Adipose tissue
Adipose Tissue - diagnostic imaging
Angiography
Body fat
Cardiovascular disease
Computed tomography
Computed Tomography Angiography - methods
Coronary Angiography - methods
Coronary artery
Coronary artery disease
Coronary vessels
Coronary Vessels - diagnostic imaging
Density
Diameters
Female
Heart - anatomy & histology
Heart - diagnostic imaging
Heart - physiology
Heart diseases
Heart Ventricles - diagnostic imaging
Humans
Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Nuclear Medicine
Original Article
Parameters
Radiology
Radiotherapy
Retrospective Studies
Stroke
Stroke volume
Stroke Volume - physiology
Structure-function relationships
Thickness
Vein & artery diseases
Ventricle
Ventricular Function - physiology
Wall thickness
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Summary:Purpose To determine the association of epicardial adipose tissue (EAT) volume and density with cardiac geometry and function. Methods We included 178 consecutive patients who performed coronary computed tomography angiography but were not diagnosed with coronary artery disease (CAD). The EAT volume, density, and following cardiac structure and function parameters were measured: left ventricular ejection fraction, left ventricular mass (LVM), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left ventricular stroke volume (LVSV), left ventricular end-diastolic diameter (LVEDD), interventricular septal thickness (IVST) and posterior wall thickness (PWT). All the parameters were standardized using the height 2.7 . Results A significant correlation was found between larger EAT volume and increased LVM, LVEDV, LVESV, LVSV, LVEDD, IVST and corresponding standardized indexes ( P  
ISSN:1867-1071
1867-108X
DOI:10.1007/s11604-020-00951-3