An idea to explore: Use of augmented reality for teaching three‐dimensional biomolecular structures

Biology and biochemistry students must learn to visualize and comprehend the complex three‐dimensional (3D) structures of macromolecules such as proteins or DNA. However, most tools available for teaching biomolecular structures typically operate in two dimensions. Here, we present protocols and ped...

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Bibliographic Details
Published in:Biochemistry and molecular biology education 2020-05, Vol.48 (3), p.276-282
Main Authors: Peterson, Celeste N., Tavana, Sara Z., Akinleye, Olukemi P., Johnson, Walter H., Berkmen, Melanie B.
Format: Article
Language:English
Subjects:
Augmented Reality
Biochemistry
Biochemistry - education
Biology
Biology - education
Computer Peripherals
Computer Simulation
Computer Software
Deoxyribonucleic acid
DNA
DNA structure
Genetics
Humans
Imaging, Three-Dimensional
Learning
Learning Processes
Macromolecular Substances
Macromolecules
Molecular Structure
molecular visualization
Protein Conformation
Protein structure
Proteins - chemistry
Science Instruction
Scientific Concepts
Software
Student Attitudes
Students
Teaching Methods
virtual reality
Visualization
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Summary:Biology and biochemistry students must learn to visualize and comprehend the complex three‐dimensional (3D) structures of macromolecules such as proteins or DNA. However, most tools available for teaching biomolecular structures typically operate in two dimensions. Here, we present protocols and pedagogical approaches for using immersive augmented reality (AR) visors, specifically the Microsoft HoloLens, to reinforce learning with large scale 3D holographic structures. We developed a novel workflow to render vividly colored custom biomolecules in AR visors. In addition, we developed AR exercises to review concepts relevant to protein or DNA structure and then implemented the exercises in four different biology and biochemistry courses. Surveys showed that students reported greater interest in biomolecular structures after the exercise. We also highlight some of the advantages and disadvantages of the software and hardware of this upcoming technology.
ISSN:1470-8175
1539-3429
DOI:10.1002/bmb.21341