Emergence and phylogenetic analysis of a novel Seneca Valley virus strain in the Guangxi Province of China

Senecavirus A (SVA), also known as Seneca Valley virus (SVV), is an emerging infectious pathogen which have been detected in swine herds from the Brazil, USA, Colombia, Thailand, Canada and some provinces in China, suggesting an increasing geographic distribution of this novel virus. Here, we isolat...

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Bibliographic Details
Published in:Research in veterinary science 2020-06, Vol.130, p.207-211
Main Authors: Wang, Hao, Niu, Chenxia, Nong, Zuorong, Quan, Dongqun, Chen, Ying, Kang, Ouyang, Huang, Weijian, Wei, Zuzhang
Format: Article
Language:English
Subjects:
Biosecurity
Cell culture
Cloning
Disease
Disease control
Emergence
Epidemics
Genomes
Geographical distribution
Hogs
Livestock
Maximum likelihood method
Nucleotide sequence
Nucleotides
Pathogens
Phylogenetics
Phylogeny
Polyclonal antibodies
Proteins
Seneca Valley virus
Swine
Vaccines
Valleys
Vesicular disease
Veterinary medicine
Viruses
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Summary:Senecavirus A (SVA), also known as Seneca Valley virus (SVV), is an emerging infectious pathogen which have been detected in swine herds from the Brazil, USA, Colombia, Thailand, Canada and some provinces in China, suggesting an increasing geographic distribution of this novel virus. Here, we isolated and characterized a SVV, designated SVA CH-GX-01-2018, thought to be responsible for typical vesicular lesions on the snouts and hooves of finishing pigs from a swine herds in Guangxi province, China, in August 2018. Phylogenetic analysis and sequence alignment indicated that this SVA CH-GX-01-2018 strain was closely related to the strains isolated in 2017 in Guangdong province, a neighboring province of Guangxi, South China, with 98.6% identity at the genome nucleotide level. Our findings characterized a novel SVV infection in pigs from South China and emphasize the importance of surveillance, reinforcing biosecurity measures and developing vaccines to prevent the spread of this viral pathogen. •We isolated and characterized a SVV isolate responsible for typical vesicular lesions on the hooves of pigs.•The SVV isolate shares 93.2% to 98.7% nucleotide similarities with other SVA strains.•The SVV isolate in Guangxi province in 2018 was closely related to the strains isolated in 2017 in Guangdong province, a neighboring province of Guangxi, South China.
ISSN:0034-5288
1532-2661
DOI:10.1016/j.rvsc.2020.03.020