Slow-wave activity and sigma activities are associated with psychomotor development at 8 months of age

Abstract Study Objectives The electrophysiological properties of non-rapid eye movement sleep (NREM) EEG are homeostatically modulated on global and local use-dependent levels. Furthermore, the local NREM quality reflects age-dependent brain maturation and individual, age-independent, and psychomoto...

Full description

Saved in:
Bibliographic Details
Published in:Sleep (New York, N.Y.) N.Y.), 2020-09, Vol.43 (9), p.1
Main Authors: Satomaa, Anna-Liisa, Mäkelä, Tiina, Saarenpää-Heikkilä, Outi, Kylliäinen, Anneli, Huupponen, Eero, Himanen, Sari-Leena
Format: Article
Language:English
Subjects:
Age
Cerebral Cortex
Child development
Electroencephalography
Electrophysiological Phenomena
Humans
Infant
Infants
NREM sleep
Polysomnography
Psychomotor performance
REM sleep
Sleep
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Study Objectives The electrophysiological properties of non-rapid eye movement sleep (NREM) EEG are homeostatically modulated on global and local use-dependent levels. Furthermore, the local NREM quality reflects age-dependent brain maturation and individual, age-independent, and psychomotor potential. Cortical maturation and its electrophysiological marker, Slow-wave activity (SWA), as well as sleep spindles are known to change in topography and quality during the early years of life, but their associations with psychomotor development in infants are unknown. Therefore, we aimed to evaluate the local properties of SWA and spindles (sigma power) and ascertain whether they correlate with psychomotor development in 8-month-old infants. Methods Ambulatory polysomnographies were recorded in 56 infants at 8 months of age to calculate the local SWA and sigma powers. The associations between the SWA and sigma powers and psychomotor development (Bayley-III) were examined in 36 of these infants. Results In both hemispheres, the highest SWA and sigma powers were found occipitally and centrally, respectively, with higher powers in the right hemisphere than in the left. The Bayley-III correlated with local SWA and sigma powers: the occipital SWA and centro-occipital sigma correlated with cognitive scales, and the frontal and occipital SWA and centro-occipital sigma correlated with language and fine motor scales. Most of the correlations were unilateral. Conclusions In 8-month-old infants, the NREM sleep quality shows local differences that are mostly attributable to the topical phase of brain maturation. The local NREM parameters correlate with psychomotor development.
ISSN:0161-8105
1550-9109
DOI:10.1093/sleep/zsaa061