Impact of type I and type II maternal diabetes mellitus on fetal cardiac function assessment parameters using spectral and tissue Doppler

The aim of this study was to evaluate the impact of pregestational diabetes mellitus (DM) on fetal cardiac function two-dimensional parameters using spectral and tissue Doppler. Pregnant women between 20 and 36 + 6 weeks gestation were divided into three groups: controls, type I DM, and type II DM....

Full description

Saved in:
Bibliographic Details
Published in:The International Journal of Cardiovascular Imaging 2020-07, Vol.36 (7), p.1237-1247
Main Authors: Peixoto, Alberto Borges, Bravo-valenzuela, Nathalie Jeanne Magioli, Martins, Wellington P., Słodki, Maciej, Mattar, Rosiane, Moron, Antonio Fernandes, Araujo Júnior, Edward
Format: Article
Language:English
Subjects:
Cardiac function
Cardiac Imaging
Cardiology
Contraction
Diabetes
Diabetes mellitus
Fetuses
Gestation
Health risk assessment
Heart diseases
Heart function
Heart rate
Hyperbilirubinemia
Hypoglycemia
Imaging
Medicine
Medicine & Public Health
Neonates
Original Paper
Parameter identification
Performance indices
Pregnancy
Radiology
Relaxation time
Spectra
Tissues
Ventricle
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of this study was to evaluate the impact of pregestational diabetes mellitus (DM) on fetal cardiac function two-dimensional parameters using spectral and tissue Doppler. Pregnant women between 20 and 36 + 6 weeks gestation were divided into three groups: controls, type I DM, and type II DM. The right ventricle (RV) and left ventricle (LV) annular velocity peaks were measured using spectral (E, A) and tissue (E′, A′, S′) Doppler. The myocardial performance index was calculated as (isovolumetric contraction time [ICT] + isovolumetric relaxation time [IRT])/ejection time using tissue (MPI′) and the spectral Doppler (MPI). A general linear model, with fetal heart rate as a covariant, was used to evaluate the effect of DM on the fetal heart function assessment parameters. To assess the association of type I and II DM with adverse perinatal outcomes, Fisher’s exact test was used. A receiver operating characteristic curve was used to determine the best cutoff for fetal cardiac function assessment parameters to identify the neonatal composite outcomes. The sample comprised 179 pregnant women. DM had significant effect on RV and LV A peak velocities (p = 0.026 and p = 0.011, respectively). LV ICT (p 
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-020-01821-9