Operation for locally advanced cervical cancer after concurrent chemoradiotherapy

Objective This paper aimed to discuss the scope of operation and clinical effects for locally advanced cervical cancer (LACC) after concurrent chemoradiotherapy (CCRT). Methods We retrospectively reviewed the records of 444 patients with stages IB2–IIB cervical cancer who were divided into two group...

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Bibliographic Details
Published in:International journal of clinical oncology 2020-05, Vol.25 (5), p.948-954
Main Authors: Ge, Junli, Sun, Jidong, Li, Jia, Zhang, Qianfeng, Lv, Xiaohui, Chen, Biliang
Format: Article
Language:English
Subjects:
Cancer Research
Cancer therapies
Cervical cancer
Cervix
Chemoradiotherapy
Chemotherapy
Edema
Enteritis
Infiltration
Medicine
Medicine & Public Health
Metastases
Oncology
Original Article
Patients
Radiation therapy
Surgical Oncology
Survival
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Summary:Objective This paper aimed to discuss the scope of operation and clinical effects for locally advanced cervical cancer (LACC) after concurrent chemoradiotherapy (CCRT). Methods We retrospectively reviewed the records of 444 patients with stages IB2–IIB cervical cancer who were divided into two groups whether or not they received CCRT before radical operation in our institute from January 2013 to December 2016. Patients’ characteristics, treatments, and outcomes were analyzed. Results The total efficiency (CR + PR) of the CCRT + operation group was 96.2%. Specifically, the CR rate was 9.1%, and the PR rate was 87.1%. The positive rates of cervical deep interstitial infiltration, lymphatic metastasis, and lymphangial infiltration of the operation group were significantly higher than those of the CCRT + operation group ( P  
ISSN:1341-9625
1437-7772
DOI:10.1007/s10147-019-01585-w