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Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA
In this study, we propose a linear field-programmable gate array (FPGA)-based charge measurement method by combining a charge-to-time converter (QTC) with a single-ended memory interface (SeMI) input receiver. The QTC automatically converts the input charge into a dual-slope pulse, which has a width...
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Published in: | Physics in medicine & biology 2020-08, Vol.65 (15), p.155007-155007 |
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container_title | Physics in medicine & biology |
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creator | Won, Jun Yeon Ko, Guen Bae Kim, Kyeong Yun Park, Haewook Lee, Seungeun Son, Jeong-Whan Lee, Jae Sung |
description | In this study, we propose a linear field-programmable gate array (FPGA)-based charge measurement method by combining a charge-to-time converter (QTC) with a single-ended memory interface (SeMI) input receiver. The QTC automatically converts the input charge into a dual-slope pulse, which has a width proportional to the input charge. Dual-slope pulses are directly digitized by the FPGA input/output (I/O) buffers configured with SeMI input receivers. A proof-of-concept comparator-less QTC/SeMI data acquisition (DAQ) system, consisting of 132 energy and 33 timing channels, was developed and applied to a prototype brain-dedicated positron emission tomography (PET) scanner. The PET scanner consisted of 14 sectors, each containing 2 × 1 block detectors, and each block detector yielded four energy signals and one timing signal. Because a single QTC/SeMI DAQ system can receive signals from up to eight sectors, two QTC/SeMI DAQ systems connected using high-speed gigabit transceivers were used to acquire data from the PET scanner. All crystals in the PET block detectors, consisting of dual-layer stacked lutetium oxyorthosilicate (LSO) scintillation crystal and silicon photomultiplier arrays, were clearly resolved in the flood maps with an excellent energy resolution. The PET images of hot-rod, cylindrical, and two-dimensional Hoffman brain phantoms were also acquired using the prototype PET scanner and two QTC/SeMI DAQ systems. |
doi_str_mv | 10.1088/1361-6560/ab8689 |
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The QTC automatically converts the input charge into a dual-slope pulse, which has a width proportional to the input charge. Dual-slope pulses are directly digitized by the FPGA input/output (I/O) buffers configured with SeMI input receivers. A proof-of-concept comparator-less QTC/SeMI data acquisition (DAQ) system, consisting of 132 energy and 33 timing channels, was developed and applied to a prototype brain-dedicated positron emission tomography (PET) scanner. The PET scanner consisted of 14 sectors, each containing 2 × 1 block detectors, and each block detector yielded four energy signals and one timing signal. Because a single QTC/SeMI DAQ system can receive signals from up to eight sectors, two QTC/SeMI DAQ systems connected using high-speed gigabit transceivers were used to acquire data from the PET scanner. All crystals in the PET block detectors, consisting of dual-layer stacked lutetium oxyorthosilicate (LSO) scintillation crystal and silicon photomultiplier arrays, were clearly resolved in the flood maps with an excellent energy resolution. The PET images of hot-rod, cylindrical, and two-dimensional Hoffman brain phantoms were also acquired using the prototype PET scanner and two QTC/SeMI DAQ systems.</description><identifier>ISSN: 0031-9155</identifier><identifier>ISSN: 1361-6560</identifier><identifier>EISSN: 1361-6560</identifier><identifier>DOI: 10.1088/1361-6560/ab8689</identifier><identifier>PMID: 32244244</identifier><identifier>CODEN: PHMBA7</identifier><language>eng</language><publisher>England: IOP Publishing</publisher><subject>brain PET scanner ; charge-to-time converter (QTC) ; data acquisition (DAQ) system ; FPGA-based digitizer ; time-based signal digitization</subject><ispartof>Physics in medicine & biology, 2020-08, Vol.65 (15), p.155007-155007</ispartof><rights>2020 Institute of Physics and Engineering in Medicine</rights><rights>2020 Institute of Physics and Engineering in Medicine.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c369t-8abfa12968e7abb3322cd41af7c6e2d3d562b7543cde966d2e46c3a230c1dd263</citedby><cites>FETCH-LOGICAL-c369t-8abfa12968e7abb3322cd41af7c6e2d3d562b7543cde966d2e46c3a230c1dd263</cites><orcidid>0000-0001-7623-053X ; 0000-0001-5760-2545</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32244244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Won, Jun Yeon</creatorcontrib><creatorcontrib>Ko, Guen Bae</creatorcontrib><creatorcontrib>Kim, Kyeong Yun</creatorcontrib><creatorcontrib>Park, Haewook</creatorcontrib><creatorcontrib>Lee, Seungeun</creatorcontrib><creatorcontrib>Son, Jeong-Whan</creatorcontrib><creatorcontrib>Lee, Jae Sung</creatorcontrib><title>Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA</title><title>Physics in medicine & biology</title><addtitle>PMB</addtitle><addtitle>Phys. Med. Biol</addtitle><description>In this study, we propose a linear field-programmable gate array (FPGA)-based charge measurement method by combining a charge-to-time converter (QTC) with a single-ended memory interface (SeMI) input receiver. The QTC automatically converts the input charge into a dual-slope pulse, which has a width proportional to the input charge. Dual-slope pulses are directly digitized by the FPGA input/output (I/O) buffers configured with SeMI input receivers. A proof-of-concept comparator-less QTC/SeMI data acquisition (DAQ) system, consisting of 132 energy and 33 timing channels, was developed and applied to a prototype brain-dedicated positron emission tomography (PET) scanner. The PET scanner consisted of 14 sectors, each containing 2 × 1 block detectors, and each block detector yielded four energy signals and one timing signal. Because a single QTC/SeMI DAQ system can receive signals from up to eight sectors, two QTC/SeMI DAQ systems connected using high-speed gigabit transceivers were used to acquire data from the PET scanner. All crystals in the PET block detectors, consisting of dual-layer stacked lutetium oxyorthosilicate (LSO) scintillation crystal and silicon photomultiplier arrays, were clearly resolved in the flood maps with an excellent energy resolution. The PET images of hot-rod, cylindrical, and two-dimensional Hoffman brain phantoms were also acquired using the prototype PET scanner and two QTC/SeMI DAQ systems.</description><subject>brain PET scanner</subject><subject>charge-to-time converter (QTC)</subject><subject>data acquisition (DAQ) system</subject><subject>FPGA-based digitizer</subject><subject>time-based signal digitization</subject><issn>0031-9155</issn><issn>1361-6560</issn><issn>1361-6560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp1kM1LxDAQxYMoun7cPUmOHqybjzZNj7LsqrCgBz2HNJkukbapSSvsf2_LrutFYUiG8Oa9yQ-ha0ruKZFyTrmgicgEmetSClkcodnh6RjNCOE0KWiWnaHzGD8IoVSy9BSdccbSdKwZ2ix80-mgex-SGmLEr8s3bHWvsTafg4uud77FcRt7aPAQXbvB01FDAq0FixtofNhi1_YQKm1g7LqhxwEMuC8IEfsKr14fHy7RSaXrCFf7-wK9r5Zvi6dk_fL4vHhYJ4aLok-kLitNWSEk5Los-biosSnVVW4EMMttJliZZyk3FgohLINUGK4ZJ4ZaywS_QLc73y74zwFirxoXDdS1bsEPUTEuBZMy59koJTupCT7GAJXqgmt02CpK1IRXTSzVxFLt8I4jN3v3oWzAHgZ-eP7GO9-pDz-Edvys6ppytFF0qoyQXHW2GqV3f0j_jf4G1B2Rww</recordid><startdate>20200811</startdate><enddate>20200811</enddate><creator>Won, Jun Yeon</creator><creator>Ko, Guen Bae</creator><creator>Kim, Kyeong Yun</creator><creator>Park, Haewook</creator><creator>Lee, Seungeun</creator><creator>Son, Jeong-Whan</creator><creator>Lee, Jae Sung</creator><general>IOP Publishing</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7623-053X</orcidid><orcidid>https://orcid.org/0000-0001-5760-2545</orcidid></search><sort><creationdate>20200811</creationdate><title>Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA</title><author>Won, Jun Yeon ; Ko, Guen Bae ; Kim, Kyeong Yun ; Park, Haewook ; Lee, Seungeun ; Son, Jeong-Whan ; Lee, Jae Sung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c369t-8abfa12968e7abb3322cd41af7c6e2d3d562b7543cde966d2e46c3a230c1dd263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>brain PET scanner</topic><topic>charge-to-time converter (QTC)</topic><topic>data acquisition (DAQ) system</topic><topic>FPGA-based digitizer</topic><topic>time-based signal digitization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Won, Jun Yeon</creatorcontrib><creatorcontrib>Ko, Guen Bae</creatorcontrib><creatorcontrib>Kim, Kyeong Yun</creatorcontrib><creatorcontrib>Park, Haewook</creatorcontrib><creatorcontrib>Lee, Seungeun</creatorcontrib><creatorcontrib>Son, Jeong-Whan</creatorcontrib><creatorcontrib>Lee, Jae Sung</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Physics in medicine & biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Won, Jun Yeon</au><au>Ko, Guen Bae</au><au>Kim, Kyeong Yun</au><au>Park, Haewook</au><au>Lee, Seungeun</au><au>Son, Jeong-Whan</au><au>Lee, Jae Sung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA</atitle><jtitle>Physics in medicine & biology</jtitle><stitle>PMB</stitle><addtitle>Phys. Med. Biol</addtitle><date>2020-08-11</date><risdate>2020</risdate><volume>65</volume><issue>15</issue><spage>155007</spage><epage>155007</epage><pages>155007-155007</pages><issn>0031-9155</issn><issn>1361-6560</issn><eissn>1361-6560</eissn><coden>PHMBA7</coden><abstract>In this study, we propose a linear field-programmable gate array (FPGA)-based charge measurement method by combining a charge-to-time converter (QTC) with a single-ended memory interface (SeMI) input receiver. The QTC automatically converts the input charge into a dual-slope pulse, which has a width proportional to the input charge. Dual-slope pulses are directly digitized by the FPGA input/output (I/O) buffers configured with SeMI input receivers. A proof-of-concept comparator-less QTC/SeMI data acquisition (DAQ) system, consisting of 132 energy and 33 timing channels, was developed and applied to a prototype brain-dedicated positron emission tomography (PET) scanner. The PET scanner consisted of 14 sectors, each containing 2 × 1 block detectors, and each block detector yielded four energy signals and one timing signal. Because a single QTC/SeMI DAQ system can receive signals from up to eight sectors, two QTC/SeMI DAQ systems connected using high-speed gigabit transceivers were used to acquire data from the PET scanner. All crystals in the PET block detectors, consisting of dual-layer stacked lutetium oxyorthosilicate (LSO) scintillation crystal and silicon photomultiplier arrays, were clearly resolved in the flood maps with an excellent energy resolution. The PET images of hot-rod, cylindrical, and two-dimensional Hoffman brain phantoms were also acquired using the prototype PET scanner and two QTC/SeMI DAQ systems.</abstract><cop>England</cop><pub>IOP Publishing</pub><pmid>32244244</pmid><doi>10.1088/1361-6560/ab8689</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0001-7623-053X</orcidid><orcidid>https://orcid.org/0000-0001-5760-2545</orcidid></addata></record> |
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subjects | brain PET scanner charge-to-time converter (QTC) data acquisition (DAQ) system FPGA-based digitizer time-based signal digitization |
title | Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA |
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