Transoral Laser Surgery for Adenosquamous Carcinoma of the Glottis: First Case Report and Review of the Literature

Adenosquamous carcinoma of the head and neck is a rare cancer associated with poor prognosis. Histologically, it is identified through the presence of both adenocarcinoma and squamous cell carcinoma, although it may be difficult to diagnose from initial endoscopic biopsies. We report a case of adeno...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2021-09, Vol.100 (8), p.593-596
Main Authors: Kendall, William, Dimitriadis, Panagiotis A., Tahir, Fawzia, Sionis, Sara
Format: Article
Language:English
Subjects:
Aged, 80 and over
Biopsy
Cancer
Carcinoma, Adenosquamous - pathology
Carcinoma, Adenosquamous - surgery
Case reports
Female
Glottis - pathology
Glottis - surgery
Head & neck cancer
Humans
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Laryngectomy - methods
Lasers, Gas - therapeutic use
Medical diagnosis
Mouth - surgery
Natural Orifice Endoscopic Surgery - methods
Otolaryngology
Throat cancer
Throat surgery
Treatment Outcome
Vocal Cords - surgery
Citations: Items that this one cites
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Summary:Adenosquamous carcinoma of the head and neck is a rare cancer associated with poor prognosis. Histologically, it is identified through the presence of both adenocarcinoma and squamous cell carcinoma, although it may be difficult to diagnose from initial endoscopic biopsies. We report a case of adenosquamous carcinoma of the glottis in an 82-year-old female patient who presented with progressive hoarseness of voice and in whom initial biopsies had shown only moderate to severe dysplasia. This is the first case in the literature of a primary adenosquamous carcinoma of the glottis managed successfully with a CO2 laser left type Va cordectomy. The patient remained disease-free 28 months postoperatively.
ISSN:0145-5613
1942-7522
DOI:10.1177/0145561320916576