Pristine carbon nanotube scaffolds for the growth of chondrocytes

The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unre...

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Bibliographic Details
Published in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2017-11, Vol.5 (41), p.8178-8182
Main Authors: King, Alice A. K, Matta-Domjan, Brigitta, Large, Matthew J, Matta, Csaba, Ogilvie, Sean P, Bardi, Niki, Byrne, Hugh J, Zakhidov, Anvar, Jurewicz, Izabela, Velliou, Eirini, Lewis, Rebecca, La Ragione, Roberto, Dalton, Alan B
Format: Article
Language:English
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Summary:The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties. The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes.
ISSN:2050-750X
2050-7518
DOI:10.1039/c7tb02065a