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Pristine carbon nanotube scaffolds for the growth of chondrocytes

The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unre...

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Published in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2017-11, Vol.5 (41), p.8178-8182
Main Authors: King, Alice A. K, Matta-Domjan, Brigitta, Large, Matthew J, Matta, Csaba, Ogilvie, Sean P, Bardi, Niki, Byrne, Hugh J, Zakhidov, Anvar, Jurewicz, Izabela, Velliou, Eirini, Lewis, Rebecca, La Ragione, Roberto, Dalton, Alan B
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cited_by cdi_FETCH-LOGICAL-c345t-f88494e2813342887c5be1c12bc7e2dcca5275505a53dd46f41b26ccbf9fab093
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container_end_page 8182
container_issue 41
container_start_page 8178
container_title Journal of materials chemistry. B, Materials for biology and medicine
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creator King, Alice A. K
Matta-Domjan, Brigitta
Large, Matthew J
Matta, Csaba
Ogilvie, Sean P
Bardi, Niki
Byrne, Hugh J
Zakhidov, Anvar
Jurewicz, Izabela
Velliou, Eirini
Lewis, Rebecca
La Ragione, Roberto
Dalton, Alan B
description The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties. The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes.
doi_str_mv 10.1039/c7tb02065a
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title Pristine carbon nanotube scaffolds for the growth of chondrocytes
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