A Schiff's base receptor for red fluorescence live cell imaging of Zn2+ ions in zebrafish embryos and naked eye detection of Ni2+ ions for bio-analytical applications

An interesting dual chemoreceptor (QAMP) was synthesized to quantify the presence of two environmentally as well as biologically important Zn2+/Ni2+ ions in a highly selective manner using different analytical techniques. The fluorescence profile was enhanced to 663 nm (red region) due to the format...

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Bibliographic Details
Published in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2017-05, Vol.5 (17), p.3195-3200
Main Authors: Senthil Murugan, A, Vidhyalakshmi, N, Ramesh, U, Annaraj, J
Format: Article
Language:English
Subjects:
Danio rerio
Fluorescence
Imaging
Logic
Materials selection
Mercury (metal)
Receptors
Synthesis (chemistry)
Zebrafish
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Summary:An interesting dual chemoreceptor (QAMP) was synthesized to quantify the presence of two environmentally as well as biologically important Zn2+/Ni2+ ions in a highly selective manner using different analytical techniques. The fluorescence profile was enhanced to 663 nm (red region) due to the formation of its 1 : 1 complex with Zn2+ at room temperature even in the presence of other interfering ions such as Cd2+ and Hg2+. Moreover, it exhibits excellent chromo-isomerism with Ni2+ ions. Meanwhile, this assay could be successfully oriented with molecular logic functions of AND, OR, NOR and NOT logic gates. The obtained large Stokes shift ( similar to 274 nm) value and red emission promoted this receptor as a potential tool for biological studies (e.g. live cell imaging in cancer cell line and zebrafish models).
ISSN:2050-750X
2050-7518
DOI:10.1039/c7tb00011a