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Pregnancy outcomes in women with inflammatory bowel disease: a 10‐year nationwide population‐based cohort study

Summary Background Data relating to the association between inflammatory bowel disease (IBD) and pregnancy outcomes are lacking in Korea. Aims To determine the incidence rates of pregnancy outcomes in women with IBD. Methods A nationwide population study was performed using the Korean National Healt...

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Published in:Alimentary pharmacology & therapeutics 2020-05, Vol.51 (9), p.861-869
Main Authors: Lee, Han H., Bae, Jung Min, Lee, Bo‐In, Lee, Kang‐Moon, Wie, Jeong H., Kim, Jin S., Cho, Young‐Seok, Jung, Sung‐Ae, Kim, Sang W., Choi, Hwang, Choi, Myung‐Gyu
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Language:English
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Summary:Summary Background Data relating to the association between inflammatory bowel disease (IBD) and pregnancy outcomes are lacking in Korea. Aims To determine the incidence rates of pregnancy outcomes in women with IBD. Methods A nationwide population study was performed using the Korean National Health Insurance claims database. A total of 2058 women with IBD consisting of ulcerative colitis (UC, n = 1469) and Crohn's disease (CD, n = 589) were pregnant between 2007 and 2016. We compared their incidence of pregnancy outcomes with 20 580 age‐matched controls without IBD. We also stratified the patients into those with quiescent to mild and moderate to severe IBD and compared the outcomes between them. Results The pregnancy rate of women with IBD was lower than that of women without (25.7% vs 32.3%, P 
ISSN:0269-2813
1365-2036
DOI:10.1111/apt.15654