Early net ultrafiltration rate and mortality in critically ill patients receiving continuous renal replacement therapy

Abstract Background In patients treated with continuous renal replacement therapy (CRRT), early net ultrafiltration (NUF) rates may be associated with differential outcomes. We tested whether higher early NUF rates are associated with increased mortality in CRRT patients. Methods We performed a retr...

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Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2021-06, Vol.36 (6), p.1112-1119
Main Authors: Naorungroj, Thummaporn, Neto, Ary Serpa, Zwakman-Hessels, Lara, Yanase, Fumitaka, Eastwood, Glenn, Murugan, Raghavan, Kellum, John A, Bellomo, Rinaldo
Format: Article
Language:English
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Summary:Abstract Background In patients treated with continuous renal replacement therapy (CRRT), early net ultrafiltration (NUF) rates may be associated with differential outcomes. We tested whether higher early NUF rates are associated with increased mortality in CRRT patients. Methods We performed a retrospective, observational study of all patients treated with CRRT within 14 days of intensive care unit admission. We defined the early (first 48 h) NUF rate as the volume of fluid removed per hour adjusted for patient body weight and analysed as a categorical variable (>1.75, 1.01–1.75 and
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfaa032