Zirconia-doped nanoparticles: organic coating, polymeric entrapment and application as dual-imaging agents

Zirconia nanoparticles doped with Eu , Tb and Gd ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were investi...

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Bibliographic Details
Published in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2013-01, Vol.1 (7), p.919-923
Main Authors: Rebuttini, Valentina, Pucci, Andrea, Arosio, Paolo, Bai, Xue, Locatelli, Erica, Pinna, Nicola, Lascialfari, Alessandro, Franchini, Mauro Comes
Format: Article
Language:English
Subjects:
Biology
Contrast agents
Encapsulation
Entrapment
Magnetic properties
Nanoparticles
Nanostructure
Organic coatings
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Summary:Zirconia nanoparticles doped with Eu , Tb and Gd ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were investigated, proving them to be potential dual-imaging contrast agents.
ISSN:2050-750X
2050-7518
DOI:10.1039/c2tb00208f