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Anti‐MDA5‐associated dermatomyositis

Anti‐MDA5‐associated dermatomyositis (MDA5‐associated DM) is an uncommon presentation of idiopathic inflammatory myositis, typically amyopathic, associated with rapidly progressive, treatment refractory interstitial lung disease and poor prognosis, particularly in patients with concomitant rapidly p...

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Published in:	Internal medicine journal 2020-04, Vol.50 (4), p.484-487
Main Authors:	Gupta, Rajiv, Kumar, Sunil, Gow, Peter, (Hsien‐Cheng) Chang, Leon, Yen, Linda
Format:	Article
Language:	English
Subjects:	anti‐MDA5‐associated dermatomyositis Autoantibodies cyclosporine Dermatomyositis Dermatomyositis - complications Dermatomyositis - diagnosis Dermatomyositis - drug therapy Humans Inflammation inflammatory myopathy intravenous immunoglobulins Lung diseases Lung Diseases, Interstitial - diagnostic imaging Lung Diseases, Interstitial - etiology MDA5‐associated interstitial lung disease Myositis
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container_title	Internal medicine journal
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creator	Gupta, Rajiv Kumar, Sunil Gow, Peter (Hsien‐Cheng) Chang, Leon Yen, Linda
description	Anti‐MDA5‐associated dermatomyositis (MDA5‐associated DM) is an uncommon presentation of idiopathic inflammatory myositis, typically amyopathic, associated with rapidly progressive, treatment refractory interstitial lung disease and poor prognosis, particularly in patients with concomitant rapidly progressive interstitial lung disease (RP‐ILD). We report two cases of MDA5‐associated DM with fatal outcome in one of the patients, despite ‘aggressive triple therapy’ for RP‐ILD.
doi_str_mv	10.1111/imj.14789
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source	Wiley-Blackwell Read & Publish Collection
subjects	anti‐MDA5‐associated dermatomyositis Autoantibodies cyclosporine Dermatomyositis Dermatomyositis - complications Dermatomyositis - diagnosis Dermatomyositis - drug therapy Humans Inflammation inflammatory myopathy intravenous immunoglobulins Lung diseases Lung Diseases, Interstitial - diagnostic imaging Lung Diseases, Interstitial - etiology MDA5‐associated interstitial lung disease Myositis
title	Anti‐MDA5‐associated dermatomyositis
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