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Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil
Aim Nonsyndromic cleft lip and/or palate (NSCL ± P) is the most common craniofacial birth defect. This study aims to determine demographic characteristics and the epidemiologic profile of NSCL ± P in Bahia, Brazil. Subject and methods 692 patients of three Cleft Lip and Palate Treatment Centers were...
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| Published in: | European archives of paediatric dentistry 2021-04, Vol.22 (2), p.121-127 |
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| Main Authors: | , , , , , |
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| cites | cdi_FETCH-LOGICAL-c375t-1100f0914280431e4eb24539c30b005ed32e9b33922b7ac3896c15bace5e44f73 |
| container_end_page | 127 |
| container_issue | 2 |
| container_start_page | 121 |
| container_title | European archives of paediatric dentistry |
| container_volume | 22 |
| creator | Maranhão, Samário Cintra Sá, Jamile Cangussú, Maria Cristina Teixeira Coletta, Ricardo Della Reis, Sílvia R. A. Medrado, Alena R. A. P. |
| description | Aim
Nonsyndromic cleft lip and/or palate (NSCL ± P) is the most common craniofacial birth defect. This study aims to determine demographic characteristics and the epidemiologic profile of NSCL ± P in Bahia, Brazil.
Subject and methods
692 patients of three Cleft Lip and Palate Treatment Centers were interviewed.
Results
Cleft lip and palate (CLP) was the most frequent type of oral cleft (52.8%), particularly unilateral (34.8%) and affecting the left side (
p
|
| doi_str_mv | 10.1007/s40368-020-00522-0 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2388822625</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2388822625</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-1100f0914280431e4eb24539c30b005ed32e9b33922b7ac3896c15bace5e44f73</originalsourceid><addsrcrecordid>eNp9kM1O3TAQRi1UBBT6AiyQpW5YNHQ8Eyf2sqCWVkJFqtq15TgOBHJj6sld0KfH5fIjddHVWJoz34yPEIcKThRA-5FroMZUgFABaMQKtsSesraprAH9pryNMlVDALviLfNNgVpqmx2xS4ht3RizJ358TzPfz31OqzHIlP0kwxSHhaWfe-mZUxj9EnuZR76Vgw9LyizHWS7XUfJSWjIN8tRfj_6DPM3-zzgdiO3BTxzfPdV98evL559nX6uLy_NvZ58uqkCtXipV_jCAVTUaqEnFOnZYa7KBoCuXxp4w2o7IInatD2RsE5TufIg61vXQ0r443uTe5fR7HXlxq5FDnCY_x7Rmh2SMQWxQF_T9P-hNWue5XOfQEmpdhFGhcEOFnJhzHNxdHlc-3zsF7q9xtzHuinH3aNxBGTp6il53q9i_jDwrLgBtAC6t-Srm193_iX0Aug2Jeg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2932559803</pqid></control><display><type>article</type><title>Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil</title><source>Springer Nature</source><creator>Maranhão, Samário Cintra ; Sá, Jamile ; Cangussú, Maria Cristina Teixeira ; Coletta, Ricardo Della ; Reis, Sílvia R. A. ; Medrado, Alena R. A. P.</creator><creatorcontrib>Maranhão, Samário Cintra ; Sá, Jamile ; Cangussú, Maria Cristina Teixeira ; Coletta, Ricardo Della ; Reis, Sílvia R. A. ; Medrado, Alena R. A. P.</creatorcontrib><description>Aim
Nonsyndromic cleft lip and/or palate (NSCL ± P) is the most common craniofacial birth defect. This study aims to determine demographic characteristics and the epidemiologic profile of NSCL ± P in Bahia, Brazil.
Subject and methods
692 patients of three Cleft Lip and Palate Treatment Centers were interviewed.
Results
Cleft lip and palate (CLP) was the most frequent type of oral cleft (52.8%), particularly unilateral (34.8%) and affecting the left side (
p
< 0.001). Family history of cleft was found in 27.6%, especially between cousins (49.7%;
p
< 0.001). The Salvador metropolitan area represented 45.2% of the samples, followed by Mid-South (17.7%) and Mid-North Bahia (13.9%). In the South of the state, the risk of developing CL and CLP was statistically significant (
p
= 0.03;
p
= 0.006, respectively), and in the region of Vale do São Francisco there was a significant risk of developing CLP (
p
= 0.01), both in relation to CP. Young age and alcohol use in pregnancy were associated to giving birth to children with CLP (
p
= 0.02,
p
= 0.03, respectively). The use of folate and other vitamins diminished the risk of developing CL and CLP if compared to CP (
p
= 0.009).
Conclusion
It is hoped that the results of this research may be useful in planning actions of public service that should take care of affected individuals.</description><identifier>ISSN: 1818-6300</identifier><identifier>EISSN: 1996-9805</identifier><identifier>DOI: 10.1007/s40368-020-00522-0</identifier><identifier>PMID: 32274688</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Alcohol ; Birth defects ; Brain ; Brazil - epidemiology ; Child ; Cleft Lip - epidemiology ; Cleft Palate - epidemiology ; Dentistry ; Drug use ; Female ; Hospitals ; Humans ; Medicine ; Metropolitan areas ; Original Scientific Article ; Pregnancy ; Risk Factors ; Smoking ; Urban areas ; Vitamin B ; Vitamins</subject><ispartof>European archives of paediatric dentistry, 2021-04, Vol.22 (2), p.121-127</ispartof><rights>European Academy of Paediatric Dentistry 2020</rights><rights>European Academy of Paediatric Dentistry 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-1100f0914280431e4eb24539c30b005ed32e9b33922b7ac3896c15bace5e44f73</citedby><cites>FETCH-LOGICAL-c375t-1100f0914280431e4eb24539c30b005ed32e9b33922b7ac3896c15bace5e44f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32274688$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maranhão, Samário Cintra</creatorcontrib><creatorcontrib>Sá, Jamile</creatorcontrib><creatorcontrib>Cangussú, Maria Cristina Teixeira</creatorcontrib><creatorcontrib>Coletta, Ricardo Della</creatorcontrib><creatorcontrib>Reis, Sílvia R. A.</creatorcontrib><creatorcontrib>Medrado, Alena R. A. P.</creatorcontrib><title>Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil</title><title>European archives of paediatric dentistry</title><addtitle>Eur Arch Paediatr Dent</addtitle><addtitle>Eur Arch Paediatr Dent</addtitle><description>Aim
Nonsyndromic cleft lip and/or palate (NSCL ± P) is the most common craniofacial birth defect. This study aims to determine demographic characteristics and the epidemiologic profile of NSCL ± P in Bahia, Brazil.
Subject and methods
692 patients of three Cleft Lip and Palate Treatment Centers were interviewed.
Results
Cleft lip and palate (CLP) was the most frequent type of oral cleft (52.8%), particularly unilateral (34.8%) and affecting the left side (
p
< 0.001). Family history of cleft was found in 27.6%, especially between cousins (49.7%;
p
< 0.001). The Salvador metropolitan area represented 45.2% of the samples, followed by Mid-South (17.7%) and Mid-North Bahia (13.9%). In the South of the state, the risk of developing CL and CLP was statistically significant (
p
= 0.03;
p
= 0.006, respectively), and in the region of Vale do São Francisco there was a significant risk of developing CLP (
p
= 0.01), both in relation to CP. Young age and alcohol use in pregnancy were associated to giving birth to children with CLP (
p
= 0.02,
p
= 0.03, respectively). The use of folate and other vitamins diminished the risk of developing CL and CLP if compared to CP (
p
= 0.009).
Conclusion
It is hoped that the results of this research may be useful in planning actions of public service that should take care of affected individuals.</description><subject>Alcohol</subject><subject>Birth defects</subject><subject>Brain</subject><subject>Brazil - epidemiology</subject><subject>Child</subject><subject>Cleft Lip - epidemiology</subject><subject>Cleft Palate - epidemiology</subject><subject>Dentistry</subject><subject>Drug use</subject><subject>Female</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Medicine</subject><subject>Metropolitan areas</subject><subject>Original Scientific Article</subject><subject>Pregnancy</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Urban areas</subject><subject>Vitamin B</subject><subject>Vitamins</subject><issn>1818-6300</issn><issn>1996-9805</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kM1O3TAQRi1UBBT6AiyQpW5YNHQ8Eyf2sqCWVkJFqtq15TgOBHJj6sld0KfH5fIjddHVWJoz34yPEIcKThRA-5FroMZUgFABaMQKtsSesraprAH9pryNMlVDALviLfNNgVpqmx2xS4ht3RizJ358TzPfz31OqzHIlP0kwxSHhaWfe-mZUxj9EnuZR76Vgw9LyizHWS7XUfJSWjIN8tRfj_6DPM3-zzgdiO3BTxzfPdV98evL559nX6uLy_NvZ58uqkCtXipV_jCAVTUaqEnFOnZYa7KBoCuXxp4w2o7IInatD2RsE5TufIg61vXQ0r443uTe5fR7HXlxq5FDnCY_x7Rmh2SMQWxQF_T9P-hNWue5XOfQEmpdhFGhcEOFnJhzHNxdHlc-3zsF7q9xtzHuinH3aNxBGTp6il53q9i_jDwrLgBtAC6t-Srm193_iX0Aug2Jeg</recordid><startdate>20210401</startdate><enddate>20210401</enddate><creator>Maranhão, Samário Cintra</creator><creator>Sá, Jamile</creator><creator>Cangussú, Maria Cristina Teixeira</creator><creator>Coletta, Ricardo Della</creator><creator>Reis, Sílvia R. A.</creator><creator>Medrado, Alena R. A. P.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>M0S</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20210401</creationdate><title>Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil</title><author>Maranhão, Samário Cintra ; Sá, Jamile ; Cangussú, Maria Cristina Teixeira ; Coletta, Ricardo Della ; Reis, Sílvia R. A. ; Medrado, Alena R. A. P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-1100f0914280431e4eb24539c30b005ed32e9b33922b7ac3896c15bace5e44f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alcohol</topic><topic>Birth defects</topic><topic>Brain</topic><topic>Brazil - epidemiology</topic><topic>Child</topic><topic>Cleft Lip - epidemiology</topic><topic>Cleft Palate - epidemiology</topic><topic>Dentistry</topic><topic>Drug use</topic><topic>Female</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Medicine</topic><topic>Metropolitan areas</topic><topic>Original Scientific Article</topic><topic>Pregnancy</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Urban areas</topic><topic>Vitamin B</topic><topic>Vitamins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maranhão, Samário Cintra</creatorcontrib><creatorcontrib>Sá, Jamile</creatorcontrib><creatorcontrib>Cangussú, Maria Cristina Teixeira</creatorcontrib><creatorcontrib>Coletta, Ricardo Della</creatorcontrib><creatorcontrib>Reis, Sílvia R. A.</creatorcontrib><creatorcontrib>Medrado, Alena R. A. P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Materials science collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of paediatric dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maranhão, Samário Cintra</au><au>Sá, Jamile</au><au>Cangussú, Maria Cristina Teixeira</au><au>Coletta, Ricardo Della</au><au>Reis, Sílvia R. A.</au><au>Medrado, Alena R. A. P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil</atitle><jtitle>European archives of paediatric dentistry</jtitle><stitle>Eur Arch Paediatr Dent</stitle><addtitle>Eur Arch Paediatr Dent</addtitle><date>2021-04-01</date><risdate>2021</risdate><volume>22</volume><issue>2</issue><spage>121</spage><epage>127</epage><pages>121-127</pages><issn>1818-6300</issn><eissn>1996-9805</eissn><abstract>Aim
Nonsyndromic cleft lip and/or palate (NSCL ± P) is the most common craniofacial birth defect. This study aims to determine demographic characteristics and the epidemiologic profile of NSCL ± P in Bahia, Brazil.
Subject and methods
692 patients of three Cleft Lip and Palate Treatment Centers were interviewed.
Results
Cleft lip and palate (CLP) was the most frequent type of oral cleft (52.8%), particularly unilateral (34.8%) and affecting the left side (
p
< 0.001). Family history of cleft was found in 27.6%, especially between cousins (49.7%;
p
< 0.001). The Salvador metropolitan area represented 45.2% of the samples, followed by Mid-South (17.7%) and Mid-North Bahia (13.9%). In the South of the state, the risk of developing CL and CLP was statistically significant (
p
= 0.03;
p
= 0.006, respectively), and in the region of Vale do São Francisco there was a significant risk of developing CLP (
p
= 0.01), both in relation to CP. Young age and alcohol use in pregnancy were associated to giving birth to children with CLP (
p
= 0.02,
p
= 0.03, respectively). The use of folate and other vitamins diminished the risk of developing CL and CLP if compared to CP (
p
= 0.009).
Conclusion
It is hoped that the results of this research may be useful in planning actions of public service that should take care of affected individuals.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32274688</pmid><doi>10.1007/s40368-020-00522-0</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1818-6300 |
| ispartof | European archives of paediatric dentistry, 2021-04, Vol.22 (2), p.121-127 |
| issn | 1818-6300 1996-9805 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2388822625 |
| source | Springer Nature |
| subjects | Alcohol Birth defects Brain Brazil - epidemiology Child Cleft Lip - epidemiology Cleft Palate - epidemiology Dentistry Drug use Female Hospitals Humans Medicine Metropolitan areas Original Scientific Article Pregnancy Risk Factors Smoking Urban areas Vitamin B Vitamins |
| title | Nonsyndromic oral clefts and associated risk factors in the state of Bahia, Brazil |
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