Central Lateral Thalamic Nucleus Stimulation Awakens Cortex via Modulation of Cross-Regional, Laminar-Specific Activity during General Anesthesia

Experiments identify cortical layer specific effects during induced arousal from general anesthesia. In this issue of Neuron, Redinbaugh et al. (2020) find evidence that central lateral thalamic nucleus electrical stimulation reactivates the cortex by restoring deep-layer firing rates and modulating...

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Bibliographic Details
Published in:Neuron (Cambridge, Mass.) Mass.), 2020-04, Vol.106 (1), p.1-3
Main Author: Schiff, Nicholas D.
Format: Article
Language:English
Subjects:
Anesthesia
Arousal
Cognitive ability
Coma
Consciousness
Electrical stimuli
Experiments
General anesthesia
Human subjects
Neural networks
Neurons
Purpura
Regions
Sleep
Thalamus
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Summary:Experiments identify cortical layer specific effects during induced arousal from general anesthesia. In this issue of Neuron, Redinbaugh et al. (2020) find evidence that central lateral thalamic nucleus electrical stimulation reactivates the cortex by restoring deep-layer firing rates and modulating feedforward and feedback connectivity. Experiments identify cortical layer specific effects during induced arousal from general anesthesia. In this issue of Neuron, Redinbaugh et al. (2020) find evidence that central lateral thalamic nucleus electrical stimulation reactivates the cortex by restoring deep-layer firing rates and modulating feedforward and feedback connectivity.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2020.02.016