Multimodality evaluation of transcatheter structural valve degeneration at long-term follow-up

We assessed the long-term hemodynamic performance of transcatheter heart valve (THV) by paired transthoracic echocardiography (TTE), and the incidence, characteristics and factors associated with THV structural valve degeneration (SVD). A total of 212 patients who underwent transcatheter aortic valv...

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Bibliographic Details
Published in:Revista española de cardiología (English ed.) 2021-03, Vol.74 (3), p.247-256
Main Authors: Ferreira-Neto, Alfredo Nunes, Rodriguez-Gabella, Tania, Guimaraes, Leonardo, Freitas-Ferraz, Afonso, Bernier, Mathieu, Figueiredo Guimaraes, Camila, Pasian, Sergio, Paradis, Jean-Michel, Delarochellière, Robert, Dumont, Eric, Mohammadi, Siamak, Kalavrouziotis, Dimitri, Côté, Mélanie, Pibarot, Philippe, Rodés-Cabau, Josep
Format: Article
Language:English
Subjects:
Aortic Valve - diagnostic imaging
Aortic Valve - surgery
Aortic Valve Stenosis - diagnosis
Aortic Valve Stenosis - surgery
Degeneración estructural de la válvula
Ecocardiografía transesofágica
Follow-Up Studies
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Hemodynamics
Humans
Implante percutáneo de válvula aórtica
Long-term follow-up
Prosthesis Design
Seguimiento a largo plazo
Structural valve degeneration
Tomografía computarizada con multidetectores
Transcatheter Aortic Valve Replacement
Transesophageal echocardiography Multidetector computed tomography
Treatment Outcome
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Summary:We assessed the long-term hemodynamic performance of transcatheter heart valve (THV) by paired transthoracic echocardiography (TTE), and the incidence, characteristics and factors associated with THV structural valve degeneration (SVD). A total of 212 patients who underwent transcatheter aortic valve replacement and had a potential follow-up >5 years with at least 1 TTE ≥ 1-year postprocedure were included. All patients had a TTE at 1 to 5 years and 36 had another one at 6 to 10 years. SVD was defined as subclinical (increase >10mmHg in mean transvalvular gradient+decrease >0.3cm2 in valve area and/or new-onset mild or moderate aortic regurgitation) and clinically relevant (increase> 20mmHg in mean transvalvular gradient+decrease> 0.6cm2 in valve area and/or new-onset moderate-to-severe aortic regurgitation). Fifteen patients had a transesophageal echocardiography at the time of SVD diagnosis, and 85 an opportunistic computed tomography examination at 1 (0.5-2) years. Transvalvular mean gradient increased and valve area decreased over time (P
ISSN:1885-5857
1885-5857
DOI:10.1016/j.rec.2020.02.002