PET Perfusion and Flow Assessment: Tomorrows’ Technology Today

Quantitative myocardial perfusion PET/CT imaging is one of the most accurate tests for diagnosis and risk stratification of patients with suspected or known CAD. The test provides a comprehensive evaluation of patients with ischemic heart disease including quantitative assessments of regional myocar...

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Bibliographic Details
Published in:Seminars in nuclear medicine 2020-05, Vol.50 (3), p.227-237
Main Author: Di Carli, Marcelo F.
Format: Article
Language:English
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Summary:Quantitative myocardial perfusion PET/CT imaging is one of the most accurate tests for diagnosis and risk stratification of patients with suspected or known CAD. The test provides a comprehensive evaluation of patients with ischemic heart disease including quantitative assessments of regional myocardial perfusion, LV volumes and ejection fraction, calcified atherosclerotic burden, and myocardial blood flow and flow reserve (MFR). A normal stress myocardial blood flow and MFR (>2.0) has a very high negative predictive value and reliably excludes high-risk obstructive CAD. A global normal MFR (>2.0) identifies patients at consistently lower clinical risk. Conversely, a severely reduced MFR (
ISSN:0001-2998
1558-4623
DOI:10.1053/j.semnuclmed.2020.02.001