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Impact of physical performance on prognosis among patients with heart failure: Systematic review and meta-analysis

•A total of 22 studies with 10,368 patients with heart failure were included in this review.•Physical performance was strongly correlated with prognosis.•The six-minute walk distance test was most frequently used.•Short physical performance battery and walking speed were frequently used among patien...

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Bibliographic Details
Published in:Journal of cardiology 2020-08, Vol.76 (2), p.139-146
Main Authors: Yamamoto, Shuhei, Yamaga, Takayoshi, Nishie, Kenichi, Sakai, Yasunari, ishida, Takaaki, Oka, Keiko, Ikegami, Shota, Horiuchi, Hiroshi
Format: Article
Language:English
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Summary:•A total of 22 studies with 10,368 patients with heart failure were included in this review.•Physical performance was strongly correlated with prognosis.•The six-minute walk distance test was most frequently used.•Short physical performance battery and walking speed were frequently used among patients with a higher mean age. This study aimed to clarify the relationship between physical performance and prognosis of patients with heart failure using a meta-analysis given the inconsistencies in published studies regarding the same. A total of 22 studies with 10,368 patients were included in this review. Hazard ratios were used for analysis, while meta-analysis was performed using the inverse-variance method. Among all physical performance tests reported in the literature, the six-minute walk distance (6MD) test was most frequently used. However, short physical performance battery (SPPB) and walking speed were more frequently used as outcomes among studies investigating patients with a higher mean age. The results of our meta-analysis showed that 6MD cut-off values were significantly associated with mortality [hazard ratio (HR), 2.04; 95% confidence interval (CI), 1.48–2.83; p
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2020.02.022