Multicenter Cryptococcal Antigen Screening of HIV-Infected Patients in Iran

Early diagnosis and targeted preemptive antifungal treatment are crucial in reducing cryptococcal meningitis (CM)-related mortality in individuals living with human immunodeficiency virus (HIV). The present study was performed to determine cryptococcal antigenemia and outcomes among HIV-infected pat...

Full description

Saved in:
Bibliographic Details
Published in:Current microbiology 2020-08, Vol.77 (8), p.1667-1672
Main Authors: Bandalizadeh, Zainab, Shokohi, Tahereh, Moosazadeh, Mahmood, Keikha, Nasser, Seyedpor, Hossein, Rabie Rudsari, Mehdi, Babamahmoudi, Farhang, Ghasemian, Roya, Mardani, Masoud, Javanian, Mostafa, Soleimanpour, Saman, Sefidgar, Ali Asghar, Shokri, Mehran, Gouya, Mohammad Mehdi, Seyedmousavi, Seyedmojtaba
Format: Article
Language:English
Subjects:
Adolescent
Adult
AIDS-Related Opportunistic Infections - diagnosis
AIDS-Related Opportunistic Infections - epidemiology
AIDS-Related Opportunistic Infections - microbiology
Antigenemia
Antigens
Antigens, Fungal - blood
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Biomedical and Life Sciences
Biotechnology
CD4 antigen
CD4 Lymphocyte Count
Child
Cryptococcosis - diagnosis
Cryptococcosis - epidemiology
Cryptococcus - isolation & purification
Drug therapy
Female
Fungicides
HIV
HIV Infections - complications
HIV Infections - epidemiology
HIV Infections - microbiology
Human immunodeficiency virus
Humans
Iran - epidemiology
Life Sciences
Male
Mass Screening
Meningitis
Microbiology
Middle Aged
Point-of-Care Systems
Preempting
Prevalence
Prospective Studies
Viruses
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Early diagnosis and targeted preemptive antifungal treatment are crucial in reducing cryptococcal meningitis (CM)-related mortality in individuals living with human immunodeficiency virus (HIV). The present study was performed to determine cryptococcal antigenemia and outcomes among HIV-infected patients in Iran. This multicenter prospective study was conducted between October 2016 and December 2018. For the purpose of the study, blood samples were randomly collected from 177 profoundly immunosuppressed (CD4+ counts 
ISSN:0343-8651
1432-0991
DOI:10.1007/s00284-020-01970-z