Determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin based on SERS substrates composited of Au nanoparticles supported on twice-oxidized graphene oxide

• Published in: Mikrochimica acta (1966) 2020-05, Vol.187 (5), p.283-283, Article 283
• Main Authors: Cheng, Jie, Fan, Mengdie, Wang, Peilong, Su, Xiao-Ou
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Dioxin; Dioxins; Gold; Graphene; Graphite; Herbicides; Microengineering; Milk; Nanochemistry; Nanoparticles; Nanotechnology; Original Paper; Pretreatment; Raman spectroscopy; Substrates
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-020-04269-9

A surface-enhanced Raman spectroscopy (SERS) substrate consisting of Au nanoparticles supported on twice-oxidized graphene oxide (ro-GO) for the determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was prepared. The Raman shift at △ v  = 779, 993, and 1203 cm −1 was collected on the excitation condition of λ  = 785 nm for the qualitative identification of 2,3,7,8-TCDD in milk. The peak at △ v  = 1203 cm −1 was selected as the characteristic peak for quantitation. The quantitation calculation was realized in the concentration range 10 to 100 ng mL −1 with a limit of detection of 3.24 ng mL −1 in milk samples. The average recoveries of 2,3,7,8-TCDD in milk were 60.6–68.6% with relative standard deviations less than 6.4%. The long-term stability of the substrates was approximately 180 days at 4 °C. Further, the SERS method for the determination of 2,3,7,8-TCDD in milk samples based on the optimized hybrid SERS substrate and corresponding pre-treatment procedure is proposed. Graphical abstract Schematic representation of surface-enhanced Raman spectroscopy (SERS) determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) in milk samples by Au nanoparticles supported on twice-oxidized graphene oxide (ro-GO/AuNP) as a substrate.