Self-reported sleep quality is associated with central hemodynamics in healthy individuals

Background Insufficient sleep is associated with arterial stiffness and elevated cardiovascular disease risk. Central hemodynamics are influenced by arterial stiffness, yet independently predict cardiovascular risk. Relationships between sleep characteristics and central hemodynamic parameters are l...

Full description

Saved in:
Bibliographic Details
Published in:Sleep & breathing 2020-09, Vol.24 (3), p.1083-1088
Main Authors: Culver, Meral N., Langan, Sean P., Carreker, Jadeon, Flatt, Andrew A., Ratchford, Stephen M., Grosicki, Gregory J.
Format: Article
Language:English
Subjects:
Blood
Body mass index
Cardiovascular disease
Cardiovascular diseases
Dentistry
Fasting
Glucose
Glucose metabolism
Hemodynamics
Internal Medicine
Laboratory testing
Medicine
Medicine & Public Health
Neurology
Otorhinolaryngology
Pediatrics
Pneumology/Respiratory System
Quality
Regression analysis
Sleep
Sleep Breathing Physiology and Disorders • Short Communication
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Insufficient sleep is associated with arterial stiffness and elevated cardiovascular disease risk. Central hemodynamics are influenced by arterial stiffness, yet independently predict cardiovascular risk. Relationships between sleep characteristics and central hemodynamic parameters are largely unexplored. We aimed to characterize the relationship between self-reported sleep quality and central hemodynamics in healthy individuals. To explore the secondary hypothesis that impairments in glucose metabolism may underlie relationships between sleep and central hemodynamic variables, we also explored associations between self-reported sleep quality and fasting blood glucose values. Methods Thirty-one healthy study subjects (20 to 69 years, 17 men) were free from metabolic or cardiovascular disease and did not take sleep medication. Self-reported sleep quality was obtained using the Pittsburgh Sleep Quality Index (PSQI) with normal sleepers defined by PSQI scores 0–5 and poor sleepers by PSQI score > 5. Relationships were assessed between PSQI, central hemodynamic profiles (systolic and diastolic blood pressures, pulse and augmentation pressures, augmentation index) estimated from oscillometric pulse wave analysis, and blood glucose values. Results Central pulse pressure was significantly elevated in poor (PSQI score > 5) compared with that in normal (PSQI scores 0–5) sleepers ( P  
ISSN:1520-9512
1522-1709
DOI:10.1007/s11325-020-02082-5