Hyperestrogenism on 18F-FDG PET/CT in a Patient With Estrogen-Producing Ovarian Clear Cell Carcinoma

ABSTRACTA 78-year-old woman was referred to the gynecologic outpatient department because she was suspected of having ovarian cancer based on an imaging study performed during a general medical examination. Further examination using F-FDG PET/CT revealed a bulky mass lesion with low FDG avidity, as...

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Bibliographic Details
Published in:Clinical nuclear medicine 2020-07, Vol.45 (7), p.e320-e322
Main Authors: Koyasu, Sho, Otani, Tomoaki, Minamiguchi, Sachiko, Nakamoto, Yuji, Togashi, Kaori
Format: Article
Language:English
Subjects:
Adenocarcinoma, Clear Cell - diagnostic imaging
Adenocarcinoma, Clear Cell - metabolism
Adenocarcinoma, Clear Cell - pathology
Aged
Estrogens - biosynthesis
Estrogens - metabolism
Female
Fluorodeoxyglucose F18
Humans
Ovarian Neoplasms - diagnostic imaging
Ovarian Neoplasms - metabolism
Ovarian Neoplasms - pathology
Positron Emission Tomography Computed Tomography
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Summary:ABSTRACTA 78-year-old woman was referred to the gynecologic outpatient department because she was suspected of having ovarian cancer based on an imaging study performed during a general medical examination. Further examination using F-FDG PET/CT revealed a bulky mass lesion with low FDG avidity, as well as surprisingly strong bilateral breast radiotracer uptake despite the patientʼs age. Thus, an estrogen-producing tumor was suspected. Bilateral salpingo-oophorectomy was performed, and surgical pathology diagnosed the tumor as clear cell carcinoma of the ovary.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000003009