Mature and immature platelets during the first week after birth and incidence of patent ductus arteriosus

Thrombocytopenia is a risk factor for patent ductus arteriosus. Immature and mature platelets exhibit distinct haemostatic properties; however, whether platelet maturity plays a role in postnatal, ductus arteriosus closure is unknown. In this observational study, counts of immature and mature platel...

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Bibliographic Details
Published in:Cardiology in the young 2020-06, Vol.30 (6), p.769-773
Main Authors: Sallmon, Hannes, Metze, Boris, Koehne, Petra, Opgen-Rhein, Bernd, Weiss, Katja, Will, Joachim C, Franke, Christina Victoria, Hansmann, Georg, Koestenberger, Martin, Bührer, Christoph, Berger, Felix, Weber, Sven C, Cremer, Malte
Format: Article
Language:English
Subjects:
Birth weight
Blood platelets
Blood Platelets - pathology
Congenital diseases
Coronary vessels
Doppler effect
Ductus Arteriosus, Patent - blood
Ductus Arteriosus, Patent - diagnosis
Ductus Arteriosus, Patent - physiopathology
Echocardiography
Female
Gestational Age
Hemodynamics
Humans
Incidence
Infant, Newborn
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - diagnosis
Infant, Premature, Diseases - physiopathology
Infant, Very Low Birth Weight - blood
Infants
Logistic Models
Low birth weight
Male
Newborn babies
Platelet Count
Platelets
Premature babies
Regression analysis
Risk analysis
Risk factors
ROC Curve
Thrombocytopenia
Weight
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Summary:Thrombocytopenia is a risk factor for patent ductus arteriosus. Immature and mature platelets exhibit distinct haemostatic properties; however, whether platelet maturity plays a role in postnatal, ductus arteriosus closure is unknown. In this observational study, counts of immature and mature platelets (=total platelet count - immature platelet count) were assessed on days 1, 3, and 7 of life in very low birth weight infants (
ISSN:1047-9511
1467-1107
DOI:10.1017/S1047951120000943