Effects of menstrual cycle on nausea and vomiting after general anesthesia

Purpose To investigate the impact of menstrual cycle on patients undergoing gynecological endoscopic surgery. Patients and methods 220 patients scheduled for gynecological endoscopic surgery under general anesthesia were selected. The patients were divided into three groups based on 3 phases of mens...

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Bibliographic Details
Published in:Journal of anesthesia 2020-08, Vol.34 (4), p.519-526
Main Authors: Zou, Lan, Miao, Shuai, Wang, Lei, Wang, GuangLei
Format: Article
Language:English
Subjects:
Analysis
Anesthesia
Anesthesia, General - adverse effects
Anesthesiology
Cisatracurium
Critical Care Medicine
Emergency Medicine
Estrogen
Female
Gynecologic Surgical Procedures - adverse effects
Humans
Intensive
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Menstrual Cycle
Menstruation
Opioids
Original Article
Pain Medicine
Postoperative Nausea and Vomiting - epidemiology
Progesterone
Sufentanil
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Summary:Purpose To investigate the impact of menstrual cycle on patients undergoing gynecological endoscopic surgery. Patients and methods 220 patients scheduled for gynecological endoscopic surgery under general anesthesia were selected. The patients were divided into three groups based on 3 phases of menstrual cycle which are the follicular phase (Group F), ovulatory phase (Group O) or luteal phase (Group L). It is based on their duration of menstruation and the last day of menstrual bleeding from the date of surgery. Primary outcomes were the incidences of early and late postoperative nausea and vomiting (PONV) in the three patient groups. Preoperative venous blood was taken to determine the estrogen and progesterone levels of the patients. Results A total of 207 patients were enrolled. The incidence of early PONV was highest in group O (22.22% vs 43.33% vs 17.86%, P  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-020-02781-z