Application of green tea extracts epigallocatechin‐3‐gallate in dental materials: Recent progress and perspectives

Because of excellent biocompatibility, antioxidant activity, and anti‐caries ability, epigallocatechin‐3‐gallate (EGCG) has been widely studied in the treatment of oral diseases, such as periodontal disease, oral cancer, and dental caries. To reach the site of the lesion or achieve sustained release...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part A 2020-12, Vol.108 (12), p.2395-2408
Main Authors: Liao, Shengnan, Tang, Yu, Chu, Chenyu, Lu, Weitong, Baligen, Bolatihan, Man, Yi, Qu, Yili
Format: Article
Language:English
Subjects:
Antioxidants
Biocompatibility
Bone growth
Controlled release
Dental caries
Dental materials
EGCG
Epigallocatechin gallate
Green tea
Inflammation
Medical treatment
Oral cancer
Oral cavity
Oral diseases
Periodontal disease
Periodontal diseases
Physical properties
Regeneration
Sustained release
Tea
Tissue engineering
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Summary:Because of excellent biocompatibility, antioxidant activity, and anti‐caries ability, epigallocatechin‐3‐gallate (EGCG) has been widely studied in the treatment of oral diseases, such as periodontal disease, oral cancer, and dental caries. To reach the site of the lesion or achieve sustained release, play the role of anti‐caries, anti‐inflammatory, or to maintain or improve the physical properties of the modified material，EGCG need to be cross‐linked or embedded with dental adhesives, barrier membranes, bone replacement materials, tissue regeneration materials, and antimicrobial anti‐caries materials to better prevent or treat oral diseases. This article reviews the applications of EGCG in oral materials, involving various areas of the oral cavity, reveals their excellent potential, and sees shortcomings in these research to promote the better development of EGCG applications in oral materials such as oral repair materials, bone tissue engineering materials and antibacterial and anti‐caries materials.
ISSN:1549-3296
1552-4965
DOI:10.1002/jbm.a.36991