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Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series
Abstract We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the pati...
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Published in: | The Journal of infectious diseases 2020-06, Vol.222 (2), p.194-197 |
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creator | Kobayashi, Ken-ichiro Kaki, Takahiro Mizuno, Shinsuke Kubo, Kenji Komiya, Nobuhiro Otsu, Satoko |
description | Abstract
We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the patients exhibited bilateral ground glass opacities on computed tomography (CT). This article also reports narrative information on the spectrum of symptoms collected directly from the patients. It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis.
We report a case series of 6 patients with COVID-19. The complaints and symptoms experienced by the patients varied. It would be difficult to triage patients with COVID-19 based on typical symptoms, although polymerase chain reaction and computed tomography are definitive in diagnosis. |
doi_str_mv | 10.1093/infdis/jiaa244 |
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We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the patients exhibited bilateral ground glass opacities on computed tomography (CT). This article also reports narrative information on the spectrum of symptoms collected directly from the patients. It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis.
We report a case series of 6 patients with COVID-19. The complaints and symptoms experienced by the patients varied. It would be difficult to triage patients with COVID-19 based on typical symptoms, although polymerase chain reaction and computed tomography are definitive in diagnosis.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/jiaa244</identifier><identifier>PMID: 32382746</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; Case reports ; Clinical Laboratory Techniques ; Computed tomography ; Coronavirus Infections - diagnosis ; Coronavirus Infections - diagnostic imaging ; Coronavirus Infections - physiopathology ; Coronaviruses ; Cough ; COVID-19 ; COVID-19 Testing ; Female ; Fever ; Humans ; Japan ; Lung - diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pharynx ; Pharynx - virology ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - diagnostic imaging ; Pneumonia, Viral - physiopathology ; Polymerase Chain Reaction ; SARS-CoV-2 ; Tomography, X-Ray Computed</subject><ispartof>The Journal of infectious diseases, 2020-06, Vol.222 (2), p.194-197</ispartof><rights>The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. 2020</rights><rights>The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c397t-b3f6fbb97b255a547a96438c7858833344e291d72b8e48b820af7152d1c706523</citedby><cites>FETCH-LOGICAL-c397t-b3f6fbb97b255a547a96438c7858833344e291d72b8e48b820af7152d1c706523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32382746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kobayashi, Ken-ichiro</creatorcontrib><creatorcontrib>Kaki, Takahiro</creatorcontrib><creatorcontrib>Mizuno, Shinsuke</creatorcontrib><creatorcontrib>Kubo, Kenji</creatorcontrib><creatorcontrib>Komiya, Nobuhiro</creatorcontrib><creatorcontrib>Otsu, Satoko</creatorcontrib><title>Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>Abstract
We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the patients exhibited bilateral ground glass opacities on computed tomography (CT). This article also reports narrative information on the spectrum of symptoms collected directly from the patients. It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis.
We report a case series of 6 patients with COVID-19. The complaints and symptoms experienced by the patients varied. It would be difficult to triage patients with COVID-19 based on typical symptoms, although polymerase chain reaction and computed tomography are definitive in diagnosis.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Betacoronavirus</subject><subject>Case reports</subject><subject>Clinical Laboratory Techniques</subject><subject>Computed tomography</subject><subject>Coronavirus Infections - diagnosis</subject><subject>Coronavirus Infections - diagnostic imaging</subject><subject>Coronavirus Infections - physiopathology</subject><subject>Coronaviruses</subject><subject>Cough</subject><subject>COVID-19</subject><subject>COVID-19 Testing</subject><subject>Female</subject><subject>Fever</subject><subject>Humans</subject><subject>Japan</subject><subject>Lung - diagnostic imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pandemics</subject><subject>Pharynx</subject><subject>Pharynx - virology</subject><subject>Pneumonia, Viral - diagnosis</subject><subject>Pneumonia, Viral - diagnostic imaging</subject><subject>Pneumonia, Viral - physiopathology</subject><subject>Polymerase Chain Reaction</subject><subject>SARS-CoV-2</subject><subject>Tomography, X-Ray Computed</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqF0TtPwzAUBWALgWgprIzIEgsMaf2MbbYqvFUJpIIYIydxqKvUCXaCxL8nVQoDC9Ndvnt0dQ8ApxhNMVJ0Zl1Z2DBbW60JY3tgjDkVURxjug_GCBESYanUCByFsEYIMRqLQzCihEoiWDwGq6Syzua6gslKe523xtvQ2jzAuoTPurXGtQG-2XYFk9rXTn9a3wV4bYPRwUCCsILWwUfdaHcF53Bp3XtloqRfMx4mW7PsI004BgelroI52c0JeL29eUnuo8XT3UMyX0Q5VaKNMlrGZZYpkRHONWdCq5hRmQvJpaSUMmaIwoUgmTRMZpIgXQrMSYFzgWJO6ARcDLmNrz86E9p0Y0Nuqko7U3chJQwhziShcU_P_9B13XnXX9crpjCRgrBeTQeV-zoEb8q08Xaj_VeKUbrtIB06SHcd9Atnu9gu25jil_88vQeXA6i75r-wb-nOj_Y</recordid><startdate>20200629</startdate><enddate>20200629</enddate><creator>Kobayashi, Ken-ichiro</creator><creator>Kaki, Takahiro</creator><creator>Mizuno, Shinsuke</creator><creator>Kubo, Kenji</creator><creator>Komiya, Nobuhiro</creator><creator>Otsu, Satoko</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20200629</creationdate><title>Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series</title><author>Kobayashi, Ken-ichiro ; Kaki, Takahiro ; Mizuno, Shinsuke ; Kubo, Kenji ; Komiya, Nobuhiro ; Otsu, Satoko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-b3f6fbb97b255a547a96438c7858833344e291d72b8e48b820af7152d1c706523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Betacoronavirus</topic><topic>Case reports</topic><topic>Clinical Laboratory Techniques</topic><topic>Computed tomography</topic><topic>Coronavirus Infections - diagnosis</topic><topic>Coronavirus Infections - diagnostic imaging</topic><topic>Coronavirus Infections - physiopathology</topic><topic>Coronaviruses</topic><topic>Cough</topic><topic>COVID-19</topic><topic>COVID-19 Testing</topic><topic>Female</topic><topic>Fever</topic><topic>Humans</topic><topic>Japan</topic><topic>Lung - diagnostic imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pandemics</topic><topic>Pharynx</topic><topic>Pharynx - virology</topic><topic>Pneumonia, Viral - diagnosis</topic><topic>Pneumonia, Viral - diagnostic imaging</topic><topic>Pneumonia, Viral - physiopathology</topic><topic>Polymerase Chain Reaction</topic><topic>SARS-CoV-2</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Ken-ichiro</creatorcontrib><creatorcontrib>Kaki, Takahiro</creatorcontrib><creatorcontrib>Mizuno, Shinsuke</creatorcontrib><creatorcontrib>Kubo, Kenji</creatorcontrib><creatorcontrib>Komiya, Nobuhiro</creatorcontrib><creatorcontrib>Otsu, Satoko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kobayashi, Ken-ichiro</au><au>Kaki, Takahiro</au><au>Mizuno, Shinsuke</au><au>Kubo, Kenji</au><au>Komiya, Nobuhiro</au><au>Otsu, Satoko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>2020-06-29</date><risdate>2020</risdate><volume>222</volume><issue>2</issue><spage>194</spage><epage>197</epage><pages>194-197</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><abstract>Abstract
We report a case series of 6 patients with confirmed coronavirus disease 2019 (COVID-19) in Wakayama prefecture, Japan. All 6 of the patients tested positive via pharyngeal swab polymerase chain reaction (PCR) tests, and 2 of the 6 were still positive at 3 weeks after onset. All of the patients exhibited bilateral ground glass opacities on computed tomography (CT). This article also reports narrative information on the spectrum of symptoms collected directly from the patients. It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis.
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subjects | Adult Aged Aged, 80 and over Betacoronavirus Case reports Clinical Laboratory Techniques Computed tomography Coronavirus Infections - diagnosis Coronavirus Infections - diagnostic imaging Coronavirus Infections - physiopathology Coronaviruses Cough COVID-19 COVID-19 Testing Female Fever Humans Japan Lung - diagnostic imaging Male Middle Aged Pandemics Pharynx Pharynx - virology Pneumonia, Viral - diagnosis Pneumonia, Viral - diagnostic imaging Pneumonia, Viral - physiopathology Polymerase Chain Reaction SARS-CoV-2 Tomography, X-Ray Computed |
title | Clinical Characteristics of Patients With Coronavirus Disease 2019 in Japan: A Single-Center Case Series |
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