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Hypertriglyceridemia-induced acute pancreatitis: A prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases

Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates the severity and related complications of AP; however, detailed analyses of large cohorts are contradictory. Our aim was to investigate the dose-dependent effect of...

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Published in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2020-06, Vol.20 (4), p.608-616
Main Authors: Mosztbacher, Dóra, Hanák, Lilla, Farkas, Nelli, Szentesi, Andrea, Mikó, Alexandra, Bajor, Judit, Sarlós, Patrícia, Czimmer, József, Vincze, Áron, Hegyi, Péter Jenő, Erőss, Bálint, Takács, Tamás, Czakó, László, Németh, Balázs Csaba, Izbéki, Ferenc, Halász, Adrienn, Gajdán, László, Hamvas, József, Papp, Mária, Földi, Ildikó, Fehér, Krisztina Eszter, Varga, Márta, Csefkó, Klára, Török, Imola, Farkas, Hunor Pál, Mickevicius, Artautas, Maldonado, Elena Ramirez, Sallinen, Ville, Novák, János, Ince, Ali Tüzün, Galeev, Shamil, Bod, Barnabás, Sümegi, János, Pencik, Petr, Dubravcsik, Zsolt, Illés, Dóra, Gódi, Szilárd, Kui, Balázs, Márta, Katalin, Pécsi, Dániel, Varjú, Péter, Szakács, Zsolt, Darvasi, Erika, Párniczky, Andrea, Hegyi, Péter
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Language:English
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Summary:Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates the severity and related complications of AP; however, detailed analyses of large cohorts are contradictory. Our aim was to investigate the dose-dependent effect of hypertriglyceridemia on AP. AP patients over 18 years old who underwent triglyceride measurement within the initial three days were included into our cohort analysis from a prospective international, multicenter AP registry operated by the Hungarian Pancreatic Study Group. Data on 716 AP cases were analyzed. Six groups were created based on the highest triglyceride level (
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2020.03.018