Does platelet-rich fibrin increase stability of the maxilla following Le Fort I osteotomy? A single-blind clinical trial study

This single-blind clinical trial study aimed to assess the efficacy of platelet-rich fibrin (PRF) in increasing stability following Le Fort I osteotomy for maxillary advancement. Patients who underwent Le Fort I osteotomy for maxillary advancement were assigned randomly into two groups: in group 1 (...

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Bibliographic Details
Published in:Journal of cranio-maxillo-facial surgery 2020-06, Vol.48 (6), p.531-535
Main Authors: Tabrizi, Reza, Mirmohammad Sadeghi, Hassan, Bakhshaei, Pedram, Ozkan, Birkan Taha
Format: Article
Language:English
Subjects:
Cephalometry
Humans
Le fort
Maxilla
Osteotomy
Osteotomy, Le Fort
Platelet-Rich Fibrin
Relapse
Single-Blind Method
Treatment Outcome
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Summary:This single-blind clinical trial study aimed to assess the efficacy of platelet-rich fibrin (PRF) in increasing stability following Le Fort I osteotomy for maxillary advancement. Patients who underwent Le Fort I osteotomy for maxillary advancement were assigned randomly into two groups: in group 1 (the study group, n = 22) PRF was placed in the osteotomy sites following fixation, while no PRF was used in group 2 (the control group, n = 22). Lateral cephalograms obtained preoperatively (T0), immediately after surgery (T1), and 1 year after surgery (T2) were compared between the two groups, and the amount of relapse was determined. The amount of maxillary change (relapse) at the A point in relation to the x-axis was 0.45 ± 0.67 mm in group 1 and 1.86 ± 0.56 mm in group 2. There was a significant difference in mean relapse in relation to the x-axis between the two groups 12 months after osteotomy (p 
ISSN:1010-5182
1878-4119
DOI:10.1016/j.jcms.2020.04.007