Echocardiography and MRI parameters associated with exercise capacity in patients after the arterial switch operation

•Patients with an arterial switch circulation frequently experience reduced exercise capacity.•Main pulmonary artery stenosis and increased right ventricular pressure are associated with reduced exercise capacity.•Pulmonary artery parameters are key to monitor during follow-up of patients after arte...

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Bibliographic Details
Published in:Journal of cardiology 2020-09, Vol.76 (3), p.280-286
Main Authors: Warmerdam, Evangeline G., Magni, Francesca, Leiner, Tim, Doevendans, Pieter A., Sieswerda, Gertjan T., van Wijk, Sebastiaan W., Breur, Hans M., Driesen, Bart W., Grotenhuis, Heynric B., Takken, Tim
Format: Article
Language:English
Subjects:
Adolescent
Adult
Arterial Switch Operation - adverse effects
Cardiac magnetic resonance
Echocardiography
Exercise Test
Exercise Tolerance - physiology
Female
Humans
Magnetic Resonance Angiography
Male
Postoperative Complications - diagnostic imaging
Postoperative Complications - etiology
Postoperative Complications - physiopathology
Postoperative Period
Retrospective Studies
Stenosis, Pulmonary Artery - diagnostic imaging
Stenosis, Pulmonary Artery - etiology
Stenosis, Pulmonary Artery - physiopathology
Time Factors
Transposition of Great Vessels - physiopathology
Transposition of Great Vessels - surgery
Transposition of the great arteries
Ventricular Dysfunction, Right - diagnostic imaging
Ventricular Dysfunction, Right - etiology
Ventricular Dysfunction, Right - physiopathology
Young Adult
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Summary:•Patients with an arterial switch circulation frequently experience reduced exercise capacity.•Main pulmonary artery stenosis and increased right ventricular pressure are associated with reduced exercise capacity.•Pulmonary artery parameters are key to monitor during follow-up of patients after arterial switch operation. The arterial switch operation (ASO) for transposition of the great arteries has excellent survival, but a substantial number of patients suffer from a reduced exercise capacity. The goal of this study was to identify imaging parameters associated with a reduced exercise capacity in patients after ASO. A retrospective analysis was performed of ASO patients who underwent cardiopulmonary exercise testing (CPET) between 2007 and 2017. Reduced exercise performance was defined as a reduced workload peak (Wpeak) with Z-score
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2020.02.025