Why SLNB procedure is not currently used in early stage oral squamous cell carcinoma?

•SLNB is comparable to END in terms of Overall Survival in patients with early stage OSCC.•SLNB can provide a significant reduction in post-operative morbidity particularly in OSCC involving subsites such as the floor of the mouth.•99mTc-tilmanocept leads to identification rate for the floor of the...

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Bibliographic Details
Published in:Oral oncology 2020-10, Vol.109, p.104746-104746, Article 104746
Main Authors: Terenzi, Valentina, Follacchio, Giulia Anna, Cassoni, Andrea, Monteleone, Francesco, Nocini, Riccardo, Valentini, Valentino
Format: Article
Language:English
Subjects:
Elective neck dissection
Oral squamous cell carcinoma
Sentinel Lymph Node Biopsy
Technetium-99m-radiolabeled colloid
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Summary:•SLNB is comparable to END in terms of Overall Survival in patients with early stage OSCC.•SLNB can provide a significant reduction in post-operative morbidity particularly in OSCC involving subsites such as the floor of the mouth.•99mTc-tilmanocept leads to identification rate for the floor of the mouth subsite of 100%, with a 0% false-negative rate and high negative predictive value, reducing “shine-through” phenomenon.•SLNB in early stage OSCC patients is a reliable technique, to be performed preferentially in a multidisciplinary setting in trained centers
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2020.104746