Increased SNR in acousto-optic imaging via coded ultrasound transmission

Acousto-optic imaging (AOI) is a non-invasive method that uses acoustic modulation to map the light fluence inside biological tissue. In many AOI implementations, ultrasound pulses are used in a time-gated measurement to perform depth-resolved imaging without the need for mechanical scanning. Howeve...

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Bibliographic Details
Published in:Optics letters 2020-05, Vol.45 (10), p.2858-2861
Main Authors: Levi, Ahiad, Monin, Sagi, Hahamovich, Evgeny, Lev, Aner, Sfez, Bruno G, Rosenthal, Amir
Format: Article
Language:English
Subjects:
Acoustic mapping
Acoustic noise
Acoustics
Acousto-optics
Fluence
Imaging
Modulation
Optical Imaging - methods
Phantoms, Imaging
Signal to noise ratio
Tissues
Ultrasonic imaging
Ultrasonic Waves
Ultrasound
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Summary:Acousto-optic imaging (AOI) is a non-invasive method that uses acoustic modulation to map the light fluence inside biological tissue. In many AOI implementations, ultrasound pulses are used in a time-gated measurement to perform depth-resolved imaging without the need for mechanical scanning. However, to achieve high axial resolution, it is required that ultrasound pulses with few cycles are used, limiting the modulation strength. In this Letter, we develop a new approach to pulse-based AOI in which coded ultrasound transmission is used. In coded-transmission AOI (CT-AOI), one may achieve an axial resolution that corresponds to a single cycle, but with a signal-to-noise ratio (SNR) that scales as the square root of the number of cycles. Using CT-AOI with 79 cycles, we experimentally demonstrate over four-fold increase in SNR in comparison to a single-cycle AOI scheme.
ISSN:0146-9592
1539-4794
DOI:10.1364/OL.392617