First report of feline morbillivirus in mainland China

Feline morbillivirus (FeMV) is an emerging member of the family Paramyxoviridae that is suspected to be involved in chronic kidney disease (CKD). FeMV was first discovered in Hong Kong in 2012 and has subsequently been detected in many countries. However, the prevalence of FeMV in mainland China is...

Full description

Saved in:
Bibliographic Details
Published in:Archives of virology 2020-08, Vol.165 (8), p.1837-1841
Main Authors: Ou, JiaJun, Ye, Shaotang, Xu, Haibin, Zhao, Jijing, Ren, Zixin, Lu, Gang, Li, Shoujun
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Brief Report
Evolution
Genetic analysis
Genetic diversity
Infectious Diseases
Kidney diseases
L gene
Medical Microbiology
Phylogeny
Reverse transcription
Ribonucleic acid
RNA
Virology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Feline morbillivirus (FeMV) is an emerging member of the family Paramyxoviridae that is suspected to be involved in chronic kidney disease (CKD). FeMV was first discovered in Hong Kong in 2012 and has subsequently been detected in many countries. However, the prevalence of FeMV in mainland China is still unclear. To clarify the present status and examine the genetic diversity of FeMV in mainland China, in this study, we collected cat urine samples in veterinary hospitals in Guangdong Province in 2017 and 2018. Using reverse transcription (RT)-PCR, we found that the urine of six out of 64 cats tested positive for FeMV RNA. Sequencing and genetic analysis of the FeMV L gene showed that FeMV in mainland China is genetically diverse, and phylogenetic analysis showed that the viruses segregated into two clusters. Two isolates, GD5 and GD6, grouped in a branch that was separate from the one containing other previously reported FeMV isolates. These results will contribute to a better understanding of the evolution of FeMV in China.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-020-04649-9