Transient renal dysfunction due to rhabdomyolysis after robot-assisted radical prostatectomy

• Published in: International urology and nephrology 2020-10, Vol.52 (10), p.1877-1884
• Main Authors: Onagi, Akifumi, Haga, Nobuhiro, Tanji, Ryo, Honda, Ruriko, Matsuoka, Kanako, Hoshi, Seiji, Koguchi, Tomoyuki, Hata, Jyunya, Sato, Yuichi, Akaihata, Hidenori, Kataoka, Masao, Ogawa, Soichiro, Kojima, Yoshiyuki
• Format: Article
• Language: English
• Subjects: Medicine; Medicine & Public Health; Nephrology; Urology; Urology - Original Paper
• ISSN: 0301-1623; 1573-2584
• DOI: 10.1007/s11255-020-02500-3

Purpose The aim of the present study was to investigate whether renal dysfunction following rhabdomyolysis occurs after robot-assisted radical prostatectomy (RARP), and to investigate the factors related to rhabdomyolysis after RARP. Methods A total of 180 consecutive patients who underwent RARP at our institution were investigated. Rhabdomyolysis was defined as creatine kinase (CK) > 1050 IU/L after RARP. The association between CK and renal function after RARP was investigated, and the factors related to rhabdomyolysis after RARP were also investigated. Results Postoperative CK (407 ± 936 IU/L) was significantly higher than preoperative CK (134 ± 75 IU/L) ( p   25.7 kg/m 2 ) and longer console time (> 188 min) ( p  = 0.02 and p  = 0.005, respectively). Conclusion Temporary renal dysfunction can occur after RARP due to CK elevation. Thus, sufficient attention must be paid to renal insufficiency after elevation of CK values for several days after RARP. Because rhabdomyolysis after RARP was associated with both obesity and long console time, console time during RARP should be shortened, especially in patients with obesity.