Relationship between age at giving fortified powdered cow’s milk and cessation of breastfeeding on the nutritional status of a Chilean child cohort followed from birth to 3 years of age

Background/objectives To examine how much of the variation in weight-for-height (WHZ) z -scores were associated with age at which breastfeeding ceased and provision of fortified cow’s milk (Leche Purita Fortificada, LPF) commenced in a cohort of children studied from birth to 3 years of age. Subject...

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Bibliographic Details
Published in:European journal of clinical nutrition 2020-07, Vol.74 (7), p.1022-1028
Main Authors: Retamal, Rodrigo, Mascie-Taylor, C. G. Nicholas, Villegas, Rodrigo, Rodríguez-Osiac, Lorena
Format: Article
Language:English
Subjects:
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Age
Analysis
Birth
Body weight
Breast feeding
Breastfeeding & lactation
Children
Clinical Nutrition
Cow's milk
Epidemiology
Health aspects
Independent variables
Internal Medicine
Medicine
Medicine & Public Health
Metabolic Diseases
Milk
Nutritional status
Obesity
Overweight
Public Health
Risk analysis
Risk factors
Variance analysis
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Summary:Background/objectives To examine how much of the variation in weight-for-height (WHZ) z -scores were associated with age at which breastfeeding ceased and provision of fortified cow’s milk (Leche Purita Fortificada, LPF) commenced in a cohort of children studied from birth to 3 years of age. Subjects/methods Longitudinal data were obtained from routine medical check-ups on 8373 children from nine Chilean counties through convenience sampling. WHZ z -scores were generated at six-monthly intervals using WHO 2006 standards from birth to 3 years old (seven measurements). Age of cessation of breastfeeding and age of commencement of LPF were the independent variables. Repeated-measures ANOVA were used to analyse the changes in WHZ over the seven measurements. Binomial generalised estimating equations (GEE) were used to analyse the effect of each independent variable on the change from normal to overweight, and normal to obese over the seven measurements. Results ANOVA indicated that children given LPF milk before 3 months of age had, on average, higher mean WHZ of about 0.11 SD from 18 months of age onwards ( p  
ISSN:0954-3007
1476-5640
DOI:10.1038/s41430-020-0665-9