C-C and C-X coupling reactions of unactivated alkyl electrophiles using copper catalysis

Transition metal-catalysed cross-coupling reactions are widely used for construction of carbon-carbon and carbon-heteroatom bonds. However, compared to aryl or alkenyl electrophiles, the cross-coupling of unactivated alkyl electrophiles containing β hydrogens remains a challenge. Over the past few y...

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Bibliographic Details
Published in:Chemical Society reviews 2020-11, Vol.49 (22), p.836-864
Main Authors: Cheng, Li-Jie, Mankad, Neal P
Format: Article
Language:English
Subjects:
Aromatic compounds
Carbenes
Carbon
catalytic activity
Chemical reactions
Copper
Cross coupling
cross-coupling reactions
Grignard reagents
heterocyclic nitrogen compounds
Lewis acids
ligands
Phosphines
Reagents
society
Transition metals
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